AUTHOR'S PROFILE

Ophoff

Publications (32)

Genomics yields biological and phenotypic insights into bipolar disorder.

Journal: Nature

Publication Year: 

Authors & Co-authors:  O'Connell Kevin S KS Koromina Maria M van der Veen Tracey T Boltz Toni T David Friederike S FS Yang Jessica Mei Kay JMK Lin Keng-Han KH Wang Xin X Coleman Jonathan R I JRI Mitchell Brittany L BL

Phenotype harmonization and analysis for The Populations Underrepresented in Mental illness Association Studies (the PUMAS Project).

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Ramirez-Diaz Ana M AM Diaz-Zuluaga Ana M AM Stroud Rocky E RE Vreeker Annabel A Bitta Mary M Ivankovic Franjo F Wootton Olivia O Whiteman Cole A CA Mountcastle Hayden H Jha Shaili C SC

A blended genome and exome sequencing method captures genetic variation in an unbiased, high-quality, and cost-effective manner.

Journal: bioRxiv : the preprint server for biology

Publication Year: 

Authors & Co-authors:  Boltz Toni A TA Chu Benjamin B BB Liao Calwing C Sealock Julia M JM Ye Robert R Majara Lerato L Fu Jack M JM Service Susan S Zhan Lingyu L Medland Sarah E SE

Principal component analysis as an efficient method for capturing multivariate brain signatures of complex disorders-ENIGMA study in people with bipolar disorders and obesity.

Journal: Human brain mapping

Publication Year: 2024

Authors & Co-authors:  McWhinney Sean R SR Hlinka Jaroslav J Bakstein Eduard E Dietze Lorielle M F LMF Corkum Emily L V ELV Abé Christoph C Alda Martin M Alexander Nina N Benedetti Francesco F Berk Michael M

Rare and low-frequency coding variants alter human adult height.

Journal: Nature

Publication Year: 2017

Authors & Co-authors:  Marouli Eirini E Graff Mariaelisa M Medina-Gomez Carolina C Lo Ken Sin KS Wood Andrew R AR Kjaer Troels R TR Fine Rebecca S RS Lu Yingchang Y Schurmann Claudia C Highland Heather M HM

Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group.

Journal: Molecular psychiatry

Publication Year: 2019

Authors & Co-authors:  Hibar D P DP Westlye L T LT Doan N T NT Jahanshad N N Cheung J W JW Ching C R K CRK Versace A A Bilderbeck A C AC Uhlmann A A Mwangi B B

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 2019

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia.

Journal: Molecular psychiatry

Publication Year: 2021

Authors & Co-authors:  Sønderby Ida E IE Gústafsson Ómar Ó Doan Nhat Trung NT Hibar Derrek P DP Martin-Brevet Sandra S Abdellaoui Abdel A Ames David D Amunts Katrin K Andersson Michael M Armstrong Nicola J NJ

Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?

Journal: Biological psychiatry

Publication Year: 2019

Authors & Co-authors:  van Erp Theo G M TGM Walton Esther E Hibar Derrek P DP Schmaal Lianne L Jiang Wenhao W Glahn David C DC Pearlson Godfrey D GD Yao Nailin N Fukunaga Masaki M Hashimoto Ryota R

Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia.

Journal: Molecular psychiatry

Publication Year: 

Authors & Co-authors:  Sønderby Ida E IE Gústafsson Ómar Ó Doan Nhat Trung NT Hibar Derrek P DP Martin-Brevet Sandra S Abdellaoui Abdel A Ames David D Amunts Katrin K Andersson Michael M Armstrong Nicola J NJ

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Turcot Valérie V Lu Yingchang Y Highland Heather M HM Schurmann Claudia C Justice Anne E AE Fine Rebecca S RS Bradfield Jonathan P JP Esko Tõnu T Giri Ayush A Graff Mariaelisa M

Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition.

Journal: JAMA psychiatry

Publication Year: 2021

Authors & Co-authors:  van der Meer Dennis D Sønderby Ida E IE Kaufmann Tobias T Walters G Bragi GB Abdellaoui Abdel A Ames David D Amunts Katrin K Andersson Micael M Armstrong Nicola J NJ

Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group.

Journal: Molecular psychiatry

Publication Year: 2022

Authors & Co-authors:  Jia Tianye T Chu Congying C Liu Yun Y van Dongen Jenny J Papastergios Evangelos E Armstrong Nicola J NJ Bastin Mark E ME Carrillo-Roa Tania T den Braber Anouk A Harris Mathew M

What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group.

Journal: Human brain mapping

Publication Year: 2022

Authors & Co-authors:  Ching Christopher R K CRK Hibar Derrek P DP Gurholt Tiril P TP Nunes Abraham A Thomopoulos Sophia I SI Abé Christoph C Agartz Ingrid I Brouwer Rachel M RM Cannon Dara M DM de Zwarte Sonja M C SMC

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans.

Journal: Translational psychiatry

Publication Year: 2021

Authors & Co-authors:  Sønderby Ida E IE van der Meer Dennis D Moreau Clara C Kaufmann Tobias T Walters G Bragi GB Ellegaard Maria M Abdellaoui Abdel A Ames David D Amunts Katrin K Andersson Micael M

Association between body mass index and subcortical brain volumes in bipolar disorders-ENIGMA study in 2735 individuals.

Journal: Molecular psychiatry

Publication Year: 2022

Authors & Co-authors:  McWhinney Sean R SR Abé Christoph C Alda Martin M Benedetti Francesco F Bøen Erlend E Del Mar Bonnin Caterina C Borgers Tiana T Brosch Katharina K Canales-Rodríguez Erick J EJ Cannon Dara M DM

Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals.

Journal: Bipolar disorders

Publication Year: 2022

Authors & Co-authors:  McWhinney Sean R SR Abé Christoph C Alda Martin M Benedetti Francesco F Bøen Erlend E Del Mar Bonnin Caterina C Borgers Tiana T Brosch Katharina K Canales-Rodríguez Erick J EJ Cannon Dara M DM

Genetic variants associated with longitudinal changes in brain structure across the lifespan.

Journal: Nature neuroscience

Publication Year: 2022

Authors & Co-authors:  Brouwer Rachel M RM Klein Marieke M Grasby Katrina L KL Schnack Hugo G HG Jahanshad Neda N Teeuw Jalmar J Thomopoulos Sophia I SI Sprooten Emma E Franz Carol E CE Gogtay Nitin N

Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants.

Journal: Psychological medicine

Publication Year: 

Authors & Co-authors:  McWhinney Sean R SR Abé Christoph C Alda Martin M Benedetti Francesco F Bøen Erlend E Del Mar Bonnin Caterina C Borgers Tiana T Brosch Katharina K Canales-Rodríguez Erick J EJ Cannon Dara M DM

Beyond the Global Brain Differences: Intraindividual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers.

Journal: Biological psychiatry

Publication Year: 2023

Authors & Co-authors:  Boen Rune R Kaufmann Tobias T van der Meer Dennis D Frei Oleksandr O Agartz Ingrid I Ames David D Andersson Micael M Armstrong Nicola J NJ Artiges Eric E Atkins Joshua R JR

Common genetic variants influence human subcortical brain structures.

Journal: Nature

Publication Year: 2015

Authors & Co-authors:  Hibar Derrek P DP Stein Jason L JL Renteria Miguel E ME Arias-Vasquez Alejandro A Desrivières Sylvane S Jahanshad Neda N Toro Roberto R Wittfeld Katharina K Abramovic Lucija L Andersson Micael M

Novel genetic loci underlying human intracranial volume identified through genome-wide association.

Journal: Nature neuroscience

Publication Year: 2017

Authors & Co-authors:  Adams Hieab H H HH Hibar Derrek P DP Chouraki Vincent V Stein Jason L JL Nyquist Paul A PA Rentería Miguel E ME Trompet Stella S Arias-Vasquez Alejandro A Seshadri Sudha S Desrivières Sylvane S

Novel genetic loci associated with hippocampal volume.

Journal: Nature communications

Publication Year: 2018

Authors & Co-authors:  Hibar Derrek P DP Adams Hieab H H HHH Jahanshad Neda N Chauhan Ganesh G Stein Jason L JL Hofer Edith E Renteria Miguel E ME Bis Joshua C JC Arias-Vasquez Alejandro A Ikram M Kamran MK

Genetic architecture of subcortical brain structures in 38,851 individuals.

Journal: Nature genetics

Publication Year: 2020

Authors & Co-authors:  Satizabal Claudia L CL Adams Hieab H H HHH Hibar Derrek P DP White Charles C CC Knol Maria J MJ Stein Jason L JL Scholz Markus M Sargurupremraj Muralidharan M Jahanshad Neda N Roshchupkin Gennady V GV

Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex.

Journal: Brain imaging and behavior

Publication Year: 2018

Authors & Co-authors:  Guadalupe Mathias vanErp Whelan Zwiers Abe Abramovic Agartz Andreassen Arias-Vásquez

Analysis of shared heritability in common disorders of the brain.

Journal: Science (New York, N.Y.)

Publication Year: 2018

Authors & Co-authors:  Anttila Bulik-Sullivan Finucane Walters Bras Duncan Escott-Price Falcone Gormley

Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium.

Journal: Biological psychiatry

Publication Year: 2019

Authors & Co-authors:  van Erp Walton Hibar Schmaal Jiang Glahn Pearlson Yao Fukunaga Hashimoto

Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.

Journal: JAMA psychiatry

Publication Year: 2022

Authors & Co-authors:  Patel Parker Shin Howard

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.

Journal: Nature genetics

Publication Year: 2021

Authors & Co-authors:  Mullins Forstner O'Connell Coombes Coleman Qiao Als Bigdeli Børte Bryois

Fine-mapping genomic loci refines bipolar disorder risk genes.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Koromina Ravi Panagiotaropoulou Schilder Humphrey Braun Bidgeli Chatzinakos Coombes Kim