Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.

Journal: Genome medicine

Publication Year: 2024

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Duncan Laramie E LE Polimanti Renato R Aaronson Cindy C

Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia.

Journal: Biological psychiatry

Publication Year: 2019

Authors & Co-authors:  Logue Mark W MW van Rooij Sanne J H SJH Dennis Emily L EL Davis Sarah L SL Hayes Jasmeet P JP Stevens Jennifer S JS Densmore Maria M Haswell Courtney C CC Ipser Jonathan J Koch Saskia B J SBJ

Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes.

Journal: Brain, behavior, and immunity

Publication Year: 2019

Authors & Co-authors:  Breen Michael S MS Wingo Aliza P AP Koen Nastassja N Donald Kirsten A KA Nicol Mark M Zar Heather J HJ Ressler Kerry J KJ Buxbaum Joseph D JD Stein Dan J DJ

Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.

Journal: Journal of affective disorders

Publication Year: 2019

Authors & Co-authors:  van der Merwe Celia C Jahanshad Neda N Cheung Josh W JW Mufford Mary M Groenewold Nynke A NA Koen Nastassja N Ramesar Rajkumar R Dalvie Shareefa S Knowles James A JA

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Journal: Nature communications

Publication Year: 2020

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Klengel Torsten T Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Dalvie Shareefa S Duncan Laramie E LE Gelernter Joel J

Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium.

Journal: Molecular psychiatry

Publication Year: 2022

Authors & Co-authors:  Dennis Emily L EL Disner Seth G SG Fani Negar N Salminen Lauren E LE Logue Mark M Clarke Emily K EK Haswell Courtney C CC Averill Christopher L CL Baugh Lee A LA Bomyea Jessica J

Genomic influences on self-reported childhood maltreatment.

Journal: Translational psychiatry

Publication Year: 2021

Authors & Co-authors:  Dalvie Shareefa S Maihofer Adam X AX Coleman Jonathan R I JRI Bradley Bekh B Breen Gerome G Brick Leslie A LA Chen Chia-Yen CY Choi Karmel W KW Duncan Laramie E LE Guffanti Guia G

Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts.

Journal: Cell reports

Publication Year: 2021

Authors & Co-authors:  Huckins Laura M LM Chatzinakos Chris C Breen Michael S MS Hartmann Jakob J Klengel Torsten T da Silva Almeida Ana C AC Dobbyn Amanda A Girdhar Kiran K Hoffman Gabriel E GE Klengel Claudia C

Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis.

Journal: Frontiers in neuroscience

Publication Year: 

Authors & Co-authors:  Sumner Jennifer A JA Maihofer Adam X AX Michopoulos Vasiliki V Rothbaum Alex O AO Almli Lynn M LM Andreassen Ole A OA Ashley-Koch Allison E AE Baker Dewleen G DG Beckham Jean C JC Bradley Bekh B

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.

Journal: Biological psychiatry

Publication Year: 2022

Authors & Co-authors:  Maihofer Adam X AX Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Denckla Christy A CA Ketema Elizabeth E Morey Rajendra A RA Polimanti Renato R Ratanatharathorn Andrew A Torres Katy K

Remodeling of the Cortical Structural Connectome in Posttraumatic Stress Disorder: Results From the ENIGMA-PGC Posttraumatic Stress Disorder Consortium.

Journal: Biological psychiatry. Cognitive neuroscience and neuroimaging

Publication Year: 2022

Authors & Co-authors:  Sun Delin D Rakesh Gopalkumar G Clarke-Rubright Emily K EK Haswell Courtney C CC Logue Mark W MW O'Leary Erin N EN Cotton Andrew S AS Xie Hong H Dennis Emily L EL Jahanshad Neda N