AUTHOR'S PROFILE

Nievergelt

Publications (25)

Genomics yields biological and phenotypic insights into bipolar disorder.

Journal: Nature

Publication Year: 

Authors & Co-authors:  O'Connell Kevin S KS Koromina Maria M van der Veen Tracey T Boltz Toni T David Friederike S FS Yang Jessica Mei Kay JMK Lin Keng-Han KH Wang Xin X Coleman Jonathan R I JRI Mitchell Brittany L BL

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.

Journal: Genome medicine

Publication Year: 2024

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Duncan Laramie E LE Polimanti Renato R Aaronson Cindy C

Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities.

Journal: Omics : a journal of integrative biology

Publication Year: 2017

Authors & Co-authors:  Dalvie Shareefa S Koen Nastassja N McGregor Nathaniel N O'Connell Kevin K Warnich Louise L Ramesar Raj R Nievergelt Caroline M CM Stein Dan J DJ

Letter to the Editor: Posttraumatic stress disorder has genetic overlap with cardiometabolic traits.

Journal: Psychological medicine

Publication Year: 2018

Authors & Co-authors:  Sumner J A JA Duncan L E LE Wolf E J EJ Amstadter A B AB Baker D G DG Beckham J C JC Gelaye B B Hemmings S S Kimbrel N A NA Logue M W MW

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.

Journal: Molecular psychiatry

Publication Year: 2019

Authors & Co-authors:  Duncan L E LE Ratanatharathorn A A Aiello A E AE Almli L M LM Amstadter A B AB Ashley-Koch A E AE Baker D G DG Beckham J C JC Bierut L J LJ Bisson J J

Genomic Approaches to Posttraumatic Stress Disorder: The Psychiatric Genomic Consortium Initiative.

Journal: Biological psychiatry

Publication Year: 2019

Authors & Co-authors:  Nievergelt Caroline M CM Ashley-Koch Allison E AE Dalvie Shareefa S Hauser Michael A MA Morey Rajendra A RA Smith Alicia K AK Uddin Monica M

Concordance of genetic variation that increases risk for anxiety disorders and posttraumatic stress disorders and that influences their underlying neurocircuitry.

Journal: Journal of affective disorders

Publication Year: 2019

Authors & Co-authors:  van der Merwe Celia C Jahanshad Neda N Cheung Josh W JW Mufford Mary M Groenewold Nynke A NA Koen Nastassja N Ramesar Rajkumar R Dalvie Shareefa S Knowles James A JA

Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder: A Mendelian Randomization Study.

Journal: JAMA network open

Publication Year: 2020

Authors & Co-authors:  Polimanti Renato R Ratanatharathorn Andrew A Maihofer Adam X AX Choi Karmel W KW Stein Murray B MB Morey Rajendra A RA Logue Mark W MW Nievergelt Caroline M CM Stein Dan J DJ Koenen Karestan C KC

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Journal: Nature communications

Publication Year: 2020

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Klengel Torsten T Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Dalvie Shareefa S Duncan Laramie E LE Gelernter Joel J

Genomic influences on self-reported childhood maltreatment.

Journal: Translational psychiatry

Publication Year: 2021

Authors & Co-authors:  Dalvie Shareefa S Maihofer Adam X AX Coleman Jonathan R I JRI Bradley Bekh B Breen Gerome G Brick Leslie A LA Chen Chia-Yen CY Choi Karmel W KW Duncan Laramie E LE Guffanti Guia G

Dissecting the genetic association of C-reactive protein with PTSD, traumatic events, and social support.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Publication Year: 2021

Authors & Co-authors:  Muniz Carvalho Carolina C Wendt Frank R FR Maihofer Adam X AX Stein Dan J DJ Stein Murray B MB Sumner Jennifer A JA Hemmings Sian M J SMJ Nievergelt Caroline M CM Koenen Karestan C KC Gelernter Joel J

Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts.

Journal: Cell reports

Publication Year: 2021

Authors & Co-authors:  Huckins Laura M LM Chatzinakos Chris C Breen Michael S MS Hartmann Jakob J Klengel Torsten T da Silva Almeida Ana C AC Dobbyn Amanda A Girdhar Kiran K Hoffman Gabriel E GE Klengel Claudia C

Gene-environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach.

Journal: The lancet. Psychiatry

Publication Year: 2021

Authors & Co-authors:  Warrier Varun V Kwong Alex S F ASF Luo Mannan M Dalvie Shareefa S Croft Jazz J Sallis Hannah M HM Baldwin Jessie J Munafò Marcus R MR Nievergelt Caroline M CM Grant Andrew J AJ

Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis.

Journal: Frontiers in neuroscience

Publication Year: 

Authors & Co-authors:  Sumner Jennifer A JA Maihofer Adam X AX Michopoulos Vasiliki V Rothbaum Alex O AO Almli Lynn M LM Andreassen Ole A OA Ashley-Koch Allison E AE Baker Dewleen G DG Beckham Jean C JC Bradley Bekh B

Disentangling sex differences in the shared genetic architecture of posttraumatic stress disorder, traumatic experiences, and social support with body size and composition.

Journal: Neurobiology of stress

Publication Year: 

Authors & Co-authors:  Muniz Carvalho Carolina C Wendt Frank R FR Pathak Gita A GA Maihofer Adam X AX Stein Dan J DJ Sumner Jennifer A JA Hemmings Sian M J SMJ Nievergelt Caroline M CM Koenen Karestan C KC Gelernter Joel J

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.

Journal: Biological psychiatry

Publication Year: 2022

Authors & Co-authors:  Maihofer Adam X AX Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Denckla Christy A CA Ketema Elizabeth E Morey Rajendra A RA Polimanti Renato R Ratanatharathorn Andrew A Torres Katy K

Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach.

Journal: Drug and alcohol dependence

Publication Year: 2022

Authors & Co-authors:  Bountress Kaitlin E KE Brick Leslie A LA Sheerin Christina C Grotzinger Andrew A Bustamante Daniel D Hawn Sage E SE Gillespie Nathan N Kirkpatrick Robert M RM Kranzler Henry H Morey Rajendra R

Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Journal: Nature communications

Publication Year: 2018

Authors & Co-authors:  Nolte Ilja M IM Munoz M Loretto ML Tragante Vinicius V Amare Azmeraw T AT Jansen Rick R Vaez Ahmad A von der Heyde Benedikt B Avery Christy L CL Bis Joshua C JC Dierckx Bram B

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.

Journal: Nature genetics

Publication Year: 2021

Authors & Co-authors:  Mullins Forstner O'Connell Coombes Coleman Qiao Als Bigdeli Børte Bryois

Migraine Prevalence, Environmental Risk, and Comorbidities in Men and Women Veterans.

Journal: JAMA network open

Publication Year: 2024

Authors & Co-authors:  Gasperi Schuster Franklin Nievergelt Stein Afari

Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes.

Journal: Translational psychiatry

Publication Year: 

Authors & Co-authors:  Maihofer Ratanatharathorn Hemmings Costenbader Michopoulos Polimanti Rothbaum Seedat Mikita