Genomics yields biological and phenotypic insights into bipolar disorder.

Journal: Nature

Publication Year: 

Authors & Co-authors:  O'Connell Kevin S KS Koromina Maria M van der Veen Tracey T Boltz Toni T David Friederike S FS Yang Jessica Mei Kay JMK Lin Keng-Han KH Wang Xin X Coleman Jonathan R I JRI Mitchell Brittany L BL

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.

Journal: Genome medicine

Publication Year: 2024

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts.

Journal: BMC medical genomics

Publication Year: 2024

Authors & Co-authors:  Wani Agaz H AH Katrinli Seyma S Zhao Xiang X Daskalakis Nikolaos P NP Zannas Anthony S AS Aiello Allison E AE Baker Dewleen G DG Boks Marco P MP Brick Leslie A LA Chen Chia-Yen CY

Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Katrinli Seyma S Wani Agaz H AH Maihofer Adam X AX Ratanatharathorn Andrew A Daskalakis Nikolaos P NP Montalvo-Ortiz Janitza J Núñez-Ríos Diana L DL Zannas Anthony S AS Zhao Xiang X Aiello Allison E AE

Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci.

Journal: medRxiv : the preprint server for health sciences

Publication Year: 

Authors & Co-authors:  Strom Nora I NI Gerring Zachary F ZF Galimberti Marco M Yu Dongmei D Halvorsen Matthew W MW Abdellaoui Abdel A Rodriguez-Fontenla Cristina C Sealock Julia M JM Bigdeli Tim T Coleman Jonathan R JR

Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder.

Journal: Nature genetics

Publication Year: 

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Duncan Laramie E LE Polimanti Renato R Aaronson Cindy C

An international research agenda for clozapine-resistant schizophrenia.

Journal: The lancet. Psychiatry

Publication Year: 2023

Authors & Co-authors:  Luykx Jurjen J JJ Gonzalez-Diaz Jairo M JM Guu Ta-Wei TW van der Horst Marte Z MZ van Dellen Edwin E Boks Marco P MP Guloksuz Sinan S DeLisi Lynn E LE Sommer Iris E IE Cummins Russel R

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Journal: Nature communications

Publication Year: 2020

Authors & Co-authors:  Nievergelt Caroline M CM Maihofer Adam X AX Klengel Torsten T Atkinson Elizabeth G EG Chen Chia-Yen CY Choi Karmel W KW Coleman Jonathan R I JRI Dalvie Shareefa S Duncan Laramie E LE Gelernter Joel J

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information.

Journal: Biological psychiatry

Publication Year: 2022

Authors & Co-authors:  Maihofer Adam X AX Choi Karmel W KW Coleman Jonathan R I JRI Daskalakis Nikolaos P NP Denckla Christy A CA Ketema Elizabeth E Morey Rajendra A RA Polimanti Renato R Ratanatharathorn Andrew A Torres Katy K

Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach.

Journal: Drug and alcohol dependence

Publication Year: 2022

Authors & Co-authors:  Bountress Kaitlin E KE Brick Leslie A LA Sheerin Christina C Grotzinger Andrew A Bustamante Daniel D Hawn Sage E SE Gillespie Nathan N Kirkpatrick Robert M RM Kranzler Henry H Morey Rajendra R

The ethics of polygenic scores in psychiatry: minefield or opportunity for patient-centered psychiatry?

Journal: Psychiatric genetics

Publication Year: 2024

Authors & Co-authors:  Wouters van der Horst Aalfs Bralten Luykx Zinkstok

Discontinuation of psychotropic medication: a synthesis of evidence across medication classes.

Journal: Molecular psychiatry

Publication Year: 

Authors & Co-authors:  Vinkers Kupka Penninx Ruhé van Gaalen van Haaren Schellekens Jauhar Ramos-Quiroga Vieta