Onset of tics in an elderly patient undergoing androgen deprivation therapy for prostate cancer: a case report.

Journal: Oxford medical case reports

Volume: 2025

Issue: 3

Year of Publication: 

Affiliated Institutions:  Department of Psychiatry and Mental Health, Kilimanjaro Christian Medical Centre, Sokoine Road, Moshi Box , Tanzania. Department of Oncology, Kilimanjaro Christian Medical Centre, Sokoine Road, Moshi Box , Tanzania.

Abstract summary 

Motor and vocal tics typically manifest during childhood. Less often, tics can occur due to the use of substances or medications which raise dopamine levels. This case report describes an unusual occurrence of tics in an elderly man undergoing androgen deprivation with Goserelin for prostate cancer. Comprehensive assessments ruled out infectious, metabolic, psychiatric, and neurological conditions. The tics resolved with low-dose Risperidone, without adverse effects. This case underscores the potential for medication-induced tics in older adults, highlighting the need for increased awareness among healthcare providers regarding the neuropsychiatric effects of cancer therapies. Future research should further investigate these phenomena and their implications for treatment strategies.

Authors & Co-authors:  Madundo Kim K Nnko Godwin G Mwakipunda Leila L Makupa Glory G Serventi Furaha F

Study Outcome 

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Statistics
Citations : 
Authors :  5
Identifiers
Doi : 10.1093/omcr/omae206
SSN : 2053-8855
Study Population
Man
Mesh Terms
Other Terms
adverse effect;androgen deprivation;prostate cancer;tic disorder;tics
Study Design
Case Study
Study Approach
Country of Study
Publication Country
England