Prevalence and risk factors of post-traumatic stress disorder and psychological distress symptoms in populations affected by Ebola in DR Congo before and during the COVID-19 pandemic.

Journal: Journal of psychosomatic research

Volume: 190

Issue: 

Year of Publication: 2025

Affiliated Institutions:  Interdisciplinary School of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada. School of Psychology, University of Ottawa, Ottawa, Ontario, Canada. Department of psychology, University of Kinshasa, Kinshasa, Congo. Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada. School of Psychology, University of Ottawa, Ottawa, Ontario, Canada; Interdisciplinary Centre for Black Health, Ottawa, Ontario, Canada; University of Ottawa Research Chair on Black Health, Ottawa, Ontario, Canada. Electronic address: jcenat@uottawa.ca.

Abstract summary 

Ebola virus disease (May 19-September 16, 2020) and COVID-19 simultaneously affected the province of Equateur in DR Congo (DRC). To date, no longitudinal studies have explored symptoms of post-traumatic stress disorder (PTSD) and psychological distress (PD) related to COVID-19 or Ebola in DRC.A representative sample of 1669 participants aged ≥18 was recruited in March-April 2019 (Time 1) and August-September 2020 (Time 2). Questionnaires assessed PTSD (PCL-5) and PD (K-10) symptoms, social support, Ebola and COVID-19 exposure and related stigmatization.Prevalence of PTSD (58.24 % in T1 to 43.74% at T2, x(1) = 5.83, p < .001) and PD symptoms (49.44 % in T1 to 28.94 % at T2, x (1) = 5.83, p < .001) decreased from the Ebola outbreak to the COVID-19 pandemic. Populations living in rural areas consistently reported higher prevalence of PTSD and PD symptoms. Generalized estimating equation (GEE) models showed that stigmatization related to Ebola is the most important predictor of both PTSD (B = 0.90, p < .0001) and PD (B = 1.22, p < .001) symptoms, followed by exposure to Ebola (B = 0.41, p < .001 and B = 0.56, p < .001). COVID-19 related stigmatization only predicted PTSD symptoms (B = 0.21, p = .009). GEE models also confirmed that PTSD (B = -0.78, p < .001) and PD (B = -1.25, p < .001) decreased from Ebola outbreak to the COVID-19 pandemic. A significant interaction was found between Ebola stigmatization and time (B = -0.40, p = .021) for PTSD, and between exposure to Ebola and time (B = -0.36, p = .026) for PD.This study confirms that Ebola related stigmatization is the most important predictor of mental health problems. Community-based strategies can address, reduce, and eliminate this issue.

Authors & Co-authors:  Dalexis Rose Darly RD Moshirian Farahi Seyed Mohammad Mahdi SMM Bukaka Jacqueline J Bekarkhanechi Farid Mansoub FM Balayulu-Makila Olea O Luyeye Noble N Cénat Jude Mary JM

Study Outcome 

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Statistics
Citations : 
Authors :  7
Identifiers
Doi : 10.1016/j.jpsychores.2025.112063
SSN : 1879-1360
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
COVID-19;DR Congo;Ebola virus disease;Post-traumatic stress disorder;Psychological distress
Study Design
Longitudinal Study
Study Approach
Country of Study
Publication Country
England