A Whole New World: Overcoming Methodological Challenges in the Post-Pandemic Recruitment of Pregnant Women at Risk of STIs.

Journal: Prevention science : the official journal of the Society for Prevention Research

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Affiliated Institutions:  Department of Family Medicine, University of Michigan, Ann Arbor, MI, USA. gtzilos@med.umich.edu. Department of Family Medicine, University of Michigan, Ann Arbor, MI, USA. Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA. Butler Center for Research, Hazelden Betty Ford Foundation, Center City, MN, USA. Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.

Abstract summary 

The impact of the COVID-19 pandemic on recruitment has been significant, including the recruitment of pregnant individuals with behavioral health risk factors. The objective of this manuscript is to highlight our response to the methodological challenges created by the pandemic and how we leveraged technology to adapt and expand our recruitment procedures for the Health Check-up for Expectant Moms, a technology-delivered behavioral skills intervention aimed at empowering and motivating pregnant women engaging in substance use and sexual health risks (e.g., condomless sex, multiple partners) to reduce their likelihood of STIs and substance use during pregnancy. After the onset of the pandemic, we transitioned from in-person recruitment to remote clinic recruitment (e.g., by phone, text messaging, and e-mail) as well as social media campaigns via Facebook® and Instagram® with a confidential web-based screening questionnaire for our study targeting pregnant women in 27 counties of Michigan. For remote recruitment, we contacted 6238 women; 1360 completed the study screening questionnaire (mean age = 31.5; SD = 4.6), 90 were eligible, and 73 were enrolled (6% eligibility). For social media recruitment, we had 2512 completing the pre-screening questionnaire. Of these, 501 (mean age = 31.9; SD = 4.6) went on to complete the full study screening questionnaire, 25 women were eligible, and 20 were enrolled (5%). Our 5% eligibility rate from our social media campaign is on par with our remote and in-clinic recruitment methods yet took far less time (15 weeks vs. 150 weeks vs. 48 weeks, respectively). Despite study recruitment challenges related to the pandemic, remote recruitment-particularly social media-was found to be a successful approach, may have a broader reach, and a cost-effective alternative to active recruitment.

Authors & Co-authors:  Tzilos Wernette Golfo G Countryman Kristina K Chen Dongru D Mmeje Okeoma O Sen Ananda A Ngo Quyen M QM Zlotnick Caron C

Study Outcome 

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Statistics
Citations :  Brogger-Mikkelsen, M., Ali, Z., Zibert, J. R., Andersen, A. D., & Thomsen, S. F. (2020). Online patient recruitment in clinical trials: Systematic review and meta-analysis. Journal of Medical Internet Research, 22(11), e22179. https://doi.org/10.2196/22179
Authors :  7
Identifiers
Doi : 10.1007/s11121-025-01775-1
SSN : 1573-6695
Study Population
Women
Mesh Terms
Other Terms
COVID-19 pandemic;STIs;pregnancy;substance use
Study Design
Study Approach
Country of Study
Publication Country
United States