Longitudinal Trends in Physical Activity Among Older Adults With and Without HIV in Uganda.

Journal: Journal of aging and health

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Affiliated Institutions:  The Roux Institute at Northeastern University, USA. Medical Practice Evaluation Center, Mongan Institute, Massachusetts General Hospital, USA. Harvard School of Dental Medicine, Boston, USA. Infectious Diseases Institute - Makerere University, Kampala, Uganda. Department of Psychiatry, Mbarara University, Uganda. School of Nursing, Bouvé College of Health Sciences, Northeastern University, USA. Harvard Medical School, USA. Department of Psychological Sciences, University of Missouri - St Louis, USA. Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, UK. Mbarara University of Science and Technology, Uganda. Kabwohe Clinical Research Centre, Uganda. Department of Neurology, Johns Hopkins University School of Medicine, USA. Department of Medicine, Indiana University School of Medicine, USA. Center for Global Health, Massachusetts General Hospital, USA. Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health San Antonio, USA.

Abstract summary 

Physical Activity (PA) and its links to frailty, quality of life (QoL), and other comorbidities in older Ugandans living with HIV remain under-explored.We analyzed data from three annual assessments of older people living with HIV (PLWH) and age- and sex-similar people not living with HIV (PnLWH). We fitted linear generalized estimating equations (GEE) regression models to estimate the correlates of PA, including demographics, frailty, QoL, HIV, and other comorbidities.We enrolled 297 PLWH and 302 PnLWH. Older age (b = -157.34, 95% CI [-222.84, -91.83]), living with HIV (b = -979.88 [95% CI: -1878.48, -81.28]), frailty (b = -3011.14 [95% CI: -4665.84, -1356.45]), and comorbidities (b = -2501.75 [95% CI: -3357.44, -1646.07]) were associated with lower overall PA. Higher general QoL (b = 89.96 [95% CI: 40.99, 138.94]) was associated with higher PA.PA interventions may support wellbeing of older people in the region, and tailored interventions should be explored.

Authors & Co-authors:  Ratnayake Aneeka A Tong Yao Y Reynolds Zahra Z Chamut Steffany S Quach Lien T LT Mbabazi Phoebe P Sagar Shruti S Maling Samuel S North Crystal M CM Passell Eliza E Yoo-Jeong Moka M Tsai Alexander C AC Paul Robert R Ritchie Christine S CS Seeley Janet J Hoeppner Susanne S SS Atwiine Flavia F Tindimwebwa Edna E Okello Samson S Nakasujja Noeline N Saylor Deanna D Greene Meredith L ML Asiimwe Stephen S Tanner Jeremy A JA Siedner Mark J MJ Olivieri-Mui Brianne B

Study Outcome 

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Citations : 
Authors :  26
Identifiers
Doi : 10.1177/08982643251314064
SSN : 1552-6887
Study Population
Male,Female
Mesh Terms
Other Terms
HIV;Uganda;frailty;older adults;physical activity;quality of life
Study Design
Longitudinal Study
Study Approach
Country of Study
Uganda
Publication Country
United States