Probiotics and Food Bioactives: Unraveling Their Impact on Gut Microbiome, Inflammation, and Metabolic Health.

Journal: Probiotics and antimicrobial proteins

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Affiliated Institutions:  Department of Biological Sciences, Faculty of Science, Taraba State University Jalingo, Jalingo, Taraba State, Nigeria. Department of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria. greatiruo@gmail.com. Department of Food Science and Technology, Faculty of Science, Delta State University of Science and Technology, Ozoro, Delta State, Nigeria. Department of Prosthetics and Orthotics Engineering, College of Engineering and Technologies, Al-Mustaqbal University, Babylon, Iraq. Department of Chemistry, College of Sciences, Al-Nahrain University, Baghdad, Iraq. Department of Science Laboratory Technology (Biochemistry Option), Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria. Department of Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria. Department of Petroleum Chemistry, Faculty of Science, Delta State University of Science and Technology, Ozoro, Nigeria. Department of Information Engineering, College of Information Engineering, Al-Nahrain University, Baghdad, Iraq. Department of Urban and Regional Planning, Faculty of Environmental Sciences, Delta State University of Science and Technology, Ozoro, Nigeria. Department of Chemical Industries, Institute of Technology-Baghdad, Middle Technical University, Baghdad, Iraq. Operational Research Centre in Healthcare, Near East University, Nicosia, Cyprus.

Abstract summary 

This review paper delves into the role of probiotics and food bioactives in influencing gut health and overall well-being, within the context of probiotics and food bioactives, emphasizing their roles in modulating inflammation, gut microbiota, and metabolic health. Probiotics are defined as live microorganisms that confer health benefits to the host, primarily through their impact on the gut microbiome; a complex community of microorganisms crucial for maintaining health. The review aims to elucidate how probiotics, incorporated into both traditional and modern food systems, can enhance gut health and address metabolic disorders. It examines the types of probiotics present in various foods and their mechanisms of action, including their effects on immune function and metabolic health. By exploring the links between probiotics and health outcomes such as digestive health, immune support, and mental health, the review identifies specific conditions where probiotics show significant promise. Hurldes such as inconsistencies in research findings, variability in probiotic strains, and dosages are addressed. The paper also suggests future research directions, including the potential for personalized probiotic interventions. The review concludes by summarizing key findings and emphasizing the critical role of probiotics in food systems for promoting overall health and mitigating metabolic diseases.

Authors & Co-authors:  Mafe Alice Njolke AN Iruoghene Edo Great G Akpoghelie Patrick Othuke PO Gaaz Tayser Sumer TS Yousif Emad E Zainulabdeen Khalid K Isoje Endurance Fegor EF Igbuku Ufuoma Augustina UA Opiti Rapheal Ajiri RA Garba Yasal Y Essaghah Arthur Efeoghene Athan AEA Ahmed Dina S DS Umar Huzaifa H

Study Outcome 

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Statistics
Citations :  Latif A, Shehzad A, Niazi S et al (2023) Probiotics: mechanism of action, health benefits and their application in food industries. Front Microbiol 14:. https://doi.org/10.3389/fmicb.2023.1216674
Authors :  13
Identifiers
Doi : 10.1007/s12602-025-10452-2
SSN : 1867-1314
Study Population
Male,Female
Mesh Terms
Other Terms
Food Bioactives;Gut Microbiome;Inflammation;Metabolic Health;Probiotics
Study Design
Study Approach
Country of Study
Publication Country
United States