Unraveling the complexity of the impact of physical exercise on male reproductive functions: a review of both sides of a coin.

Journal: Frontiers in physiology

Volume: 15

Issue: 

Year of Publication: 

Affiliated Institutions:  Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo, Nigeria. Reproductive Biology and Toxicology Research Laboratory, Oasis of Grace Hospital, Osogbo, Nigeria.

Abstract summary 

Regular exercise is widely recognized for its numerous physical and mental benefits, but its effects on male reproductive health are less understood. This review aims to summarize the current evidence on the impact of exercise on male reproduction, including reproductive hormone regulation, spermatogenesis sperm quality, and fertility. Moderate exercise improves sperm quality, increasing count, motility, and morphology, while excessive and severe exercise may have detrimental effects. Exercise positively influences fertility by reducing oxidative stress and enhancing sperm DNA integrity. Regular physical activity regulates reproductive hormones, including testosterone, follicle-stimulating hormone, and luteinizing hormone. Exercise-induced weight management and improved insulin sensitivity also contribute to better reproductive health. In conclusion, exercise has a profound impact on male reproductive health, with moderate physical activity promoting improved hormonal balance, sperm quality, and fertility. However, severe/excessive exercise exerts negative effects. These findings imply that a balanced exercise routine, usually mild to moderate, combined with a healthy lifestyle is essential for optimal male reproductive health. However, once exercise is severe and prolonged, it could impair male reproductive health. Further research is needed to understand the mechanisms underlying the exercise-reproduction relationship fully.

Authors & Co-authors:  Adelowo Olayinka Emmanuel OE Akindele Blessing Monica BM Adegbola Cecilia Adedeji CA Oyedokun Precious Adeoye PA Akhigbe Tunmise Maryanne TM Akhigbe Roland Eghoghosoa RE

Study Outcome 

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Statistics
Citations :  Adeyemi D., Arokoyo D., Hamed M., Dare A., Oyedokun P., Akhigbe R. (2024). Cardiometabolic disorder and erectile dysfunction. Cell Biochem. Biophysics 82, 1751–1762. 10.1007/s12013-024-01361-2
Authors :  6
Identifiers
Doi : 1492771
SSN : 1664-042X
Study Population
Male
Mesh Terms
Other Terms
cytokines;exercise;inflammation;male fertility;oxidative stress;physical activity;spermatogenesis;testosterone
Study Design
Study Approach
Country of Study
Publication Country
Switzerland