The Fidelity of a Pharmacy-Based Oral HIV Pre-Exposure Prophylaxis Delivery Model in Kenya.

Journal: Journal of acquired immune deficiency syndromes (1999)

Volume: 93

Issue: 5

Year of Publication: 2023

Affiliated Institutions:  Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya. Partners in Health and Research Development, Thika, Kenya. Departments of Pharmacy. Global Health. Howard University, Washington, DC. School of Public Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya; and. Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA.

Abstract summary 

HIV pre-exposure prophylaxis (PrEP) delivery at private pharmacies is a promising new differentiated service delivery model that may address barriers to PrEP delivery at public health care facilities. We measured the fidelity of this model (ie, delivery as intended) in a pilot study in Kenya.Five private, retail pharmacies in Kisumu and Thika Counties.Trained pharmacy providers delivered PrEP services, including identifying eligible clients, counseling on HIV risk, assessing PrEP safety, testing for HIV, and dispensing PrEP. Pharmacy clients completed surveys that assessed the fidelity of the services received after each visit. Standardized client actors (ie, mystery shoppers) were trained on 4 different case scripts, then made unannounced pharmacy visits, and then completed a 40-item checklist that assessed the fidelity and quality of service delivery components.From November 2020 to December 2021, 287 clients initiated and 159 (55%) refilled PrEP. At initiation, most clients were counseled on PrEP adherence (99%, 284 of 287) and potential side effects (97%, 279 of 287) and all received provider-assisted HIV self-testing before PrEP dispensing (findings consistent across refill visits). Nine standardized client actors completed 15 pharmacy visits. At each visit, most actors were asked about their behaviors associated with HIV risk (80%, 12/15) and all were counseled on PrEP safety and side effects. All actors reported that pharmacy providers treated them with respect.In this first pilot study of pharmacy-delivered PrEP services in Africa, the fidelity of service delivery was high, suggesting that trained providers at private pharmacies can deliver quality PrEP services.

Authors & Co-authors:  Omollo Victor V Asewe Magdaline M Mogere Peter P Maina Gakuo G Kuo Alexandra P AP Odoyo Josephine J Oware Kevin K Baeten Jared M JM Kohler Pamela P Owens Tamara T Bukusi Elizabeth A EA Ngure Kenneth K Ortblad Katrina F KF

Study Outcome 

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Statistics
Citations :  Baeten JM, Donnell D, Ndase P, et al. ; Partners PrEP Study Team. Antiretroviral prophylaxis for HIV prevention in heterosexual men and women. N Engl J Med. 2012;367:399–410.
Authors :  13
Identifiers
Doi : 10.1097/QAI.0000000000003208
SSN : 1944-7884
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
Study Design
Case Study
Study Approach
Country of Study
Kenya
Publication Country
United States