Coronavirus disease 2019 outcomes in a population-based cohort of people with HIV and a matched cohort of people without HIV during Omicron variant waves.

Journal: AIDS (London, England)

Volume: 38

Issue: 10

Year of Publication: 2024

Affiliated Institutions:  MAP Centre for Urban Health Solutions, Unity Health Toronto. Ottawa Hospital Research Institute, Ottawa. Dalla Lana School of Public Health, University of Toronto, Toronto. ICES, Toronto. Department of Family and Community Medicine, Temerty Faculty of Medicine. Research Institute of the McGill University Health Centre, Montreal, Quebec. CIHR Canadian HIV Trials Network. BC Centre for Disease Control. Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa. HQ Health Hub, Toronto. Department of Health Research Methods, Evidence and Impact. Public Health Agency of Canada, Ottawa. Gay Men's Sexual Health Alliance. Centre for Addiction and Mental Health. Public Health Ontario. Department of Medicine, University Health Network.

Abstract summary 

We found that rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing and reverse transcriptase (RT)-PCR-confirmed infection were approximately 50% higher in a population-based cohort of people with HIV compared with a matched cohort of people without HIV during the Omicron era (2 January 2022 to 31 March 2023) in Ontario, Canada, after controlling for age, sex, residential census tract, and country of birth. Rates of coronavirus disease 2019 (COVID-19)-related hospitalization and/or death were more than double. Differences persisted independent of vaccination, healthcare access, and COVID-19 diagnosis.

Authors & Co-authors:  Chambers Catharine C Cooper Curtis L CL Kroch Abigail E AE Buchan Sarah A SA Kendall Claire E CE Kwong Jeffrey C JC Moideddin Rahim R Nguyen Lena L Arbess Gordon G Benoit Anita C AC Costiniuk Cecilia T CT Habanyama Muluba M Janjua Naveed Z NZ Langlois Marc-André MA McCullagh John J Mbuagbaw Lawrence L Moqueet Nasheed N Nambiar Devan D Rueda Sergio S Samji Hasina H Tran Vanessa V Walmsley Sharon S Anis Aslam A Burchell Ann N AN

Study Outcome 

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Statistics
Citations :  Höft MA, Burgers WA, Riou C. The immune response to SARS-CoV-2 in people with HIV. Cell Mol Immunol 2024; 21:184–196.
Authors :  25
Identifiers
Doi : 10.1097/QAD.0000000000003922
SSN : 1473-5571
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
Study Design
Cohort Study
Study Approach
Country of Study
Publication Country
England