Correlates of HIV treatment adherence self-efficacy among adolescents and young adults living with HIV in southwestern Uganda.

Journal: PLOS global public health

Volume: 4

Issue: 9

Year of Publication: 

Affiliated Institutions:  Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda. Global Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda. Department of Pediatrics, Mbarara University of Science and Technology, Mbarara, Uganda. Department of Pediatric Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America.

Abstract summary 

Adherence to antiretroviral therapy (ART) among adolescents and young adults living with HIV (AYLHIV) in sub-Saharan Africa is sub-optimal compared to younger children and older adults. Adherence self-efficacy is one of the intrapersonal factors most strongly correlated with ART adherence. The role of adherence self-efficacy in ART adherence among AYLHIV is not well studied in Uganda. We enrolled 300 AYLHIV between October and December 2021 from an HIV clinic in southwestern Uganda. We collected information on adherence self-efficacy, HIV stigma, depression, self-management, and social skills. We used linear regression to estimate the association between adherence self-efficacy and the covariates of interest. At multivariable adjustment self-management (b = 0.29, 95% CI 0.23-0.35, p<0.001) and social skills (b = 0.16, 95% CI 0.08-0.24; p<0.001) were statistically significantly associated with adherence self-efficacy. The findings imply that interventions directed at enhancing self-management and social skills in AYLHIV may increase adherence self-efficacy and, potentially, HIV outcomes among AYLHIV.

Authors & Co-authors:  Ashaba Scholastic S Baguma Charles C Tushemereirwe Patricia P Nansera Denis D Maling Samuel S Zanon Brian C BC Tsai Alexander C AC

Study Outcome 

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Citations :  Dow DE, Shayo AM, Cunningham CK, Reddy EA. Durability of antiretroviral therapy and predictors of virologic failure among perinatally HIV-infected children in Tanzania: a four-year follow-up. BMC infectious diseases. 2014;14(1):567. doi: 10.1186/s12879-014-0567-3
Authors :  7
Identifiers
Doi : e0003600
SSN : 2767-3375
Study Population
Male,Female
Mesh Terms
Other Terms
Study Design
Study Approach
Country of Study
Uganda
Publication Country
United States