Potentially Inappropriate Medication in Older Persons With Dementia: Does a Migration Background Matter?

Journal: Journal of the American Medical Directors Association

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Affiliated Institutions:  Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of General Practice, Amsterdam, The Netherlands; Amsterdam Public Health, Health Behaviors & Chronic Diseases, Amsterdam, The Netherlands. Electronic address: b.strooij@amsterdamumc.nl. Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of General Practice, Amsterdam, The Netherlands; Amsterdam Public Health, Health Behaviors & Chronic Diseases, Amsterdam, The Netherlands. Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of General Practice, Amsterdam, The Netherlands. Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of General Practice, Amsterdam, The Netherlands; Amsterdam Public Health, Aging & Later Life, Amsterdam, The Netherlands. Department of Geriatrics, OLVG Hospital, Amsterdam, The Netherlands. Nivel, Netherlands Institute for Health Services Research, Utrecht, The Netherlands. Nivel, Netherlands Institute for Health Services Research, Utrecht, The Netherlands; Tilburg School of Social and Behavioral Sciences, Tilburg University, Tilburg, The Netherlands. Amsterdam Public Health, Aging & Later Life, Amsterdam, The Netherlands; Amsterdam UMC, Location Vrije Universiteit Amsterdam, Department of Medicine for Older People, Amsterdam, The Netherlands.

Abstract summary 

Previous research in the general population shows more potentially inappropriate medications (PIMs) among persons with a migration background compared with persons without a migration background. This study investigated the association between non-Western (nw) migration background (MB) and dementia-specific PIMs in older adults with dementia in the Netherlands.Cohort study using routinely recorded electronic health records and administrative data.Electronic health record data of general practitioners from the NIVEL-Primary Care Database, were linked to registries managed by Statistics Netherlands (2013-2014). A total of 9055 community-dwelling older adults with dementia were included, among whom 294 persons had an nw-MB from Africa, South America, or Asia, based on their country of birth.We determined the presence of dementia-specific PIM prescriptions and compared this between persons with an nw-MB and without an MB, using logistic regression analysis adjusted for follow-up time, age, sex, and total number of prescriptions. Interaction effects of potentially relevant covariates were tested. The 3 largest nw-MB groups in the Netherlands were analyzed separately.Dementia-specific PIMs were less frequently prescribed to persons with an nw-MB compared to persons without an MB with a dementia diagnosis [30.6% vs 34.4%, odds ratio (OR) 0.71, 95% CI 0.54-0.92], with especially less often a benzodiazepine prescription in the group with an nw-MB, compared to persons without an MB (15.0% vs 19.3%, OR 0.61, 95% CI 0.43-0.84). Dementia duration, living alone, household income, and degree of urbanization did not influence the associations.Among older adults with dementia in the Netherlands, persons with an nw-MB had less often a dementia-specific PIM prescription compared to persons without an MB. Whether this difference is a reflection of better quality of care, higher professional uncertainty, or less recognition of (mental) health problems in persons with an nw-MB and dementia, needs further investigation.

Authors & Co-authors:  Strooij Bianca T BT Blom Marieke T MT van Hout Hein P J HPJ Maarsingh Otto R OR Elders Petra J M PJM van Campen Jos P C M JPCM van der Heide Iris I Verheij Robert A RA Joling Karlijn J KJ

Study Outcome 

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Citations : 
Authors :  9
Identifiers
Doi : 10.1016/j.jamda.2024.105150
SSN : 1538-9375
Study Population
Male,Female
Mesh Terms
Other Terms
Dementia;health care quality;inappropriate prescribing;migration background;older adults
Study Design
Study Approach
Country of Study
Publication Country
United States