From Alzheimer's Disease to Anxiety, Epilepsy to Schizophrenia: A Comprehensive Dive Into Neuro-Psychiatric Disorders.

Journal: Cureus

Volume: 16

Issue: 4

Year of Publication: 

Affiliated Institutions:  Medicine and Surgery, Guangxi Medical University, Nanning, CHN. Medical Education, Mymensingh Medical College, Dhaka, BGD. Medicine, St. George's University, St. George's, USA. Psychiatry and Behavioral Sciences, Dow University of Health Sciences, Karachi, PAK. Geriatrics, United Lincolnshire Hospitals NHS Trust, Boston, GBR. General Practice, St. Paul's Hospital Millennium Medical College, Addis Ababa, ETH. Medical Services, Federal Democratic Republic of Ethiopia Ministry of Health, Addis Ababa, ETH. Internal Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, ETH. Internal Medicine, Allama Iqbal Medical College, Lahore, PAK. Surgery, Mayo Hospital, Lahore, PAK. Internal Medicine, Mayo Hospital, Lahore, PAK.

Abstract summary 

This comprehensive narrative review endeavors to dissect the intricate web of neuropsychiatric disorders that significantly impact cognition, emotion regulation, behavior, and mental health. With a keen focus on Alzheimer's disease (AD), anxiety disorders, epilepsy, schizophrenia, and autism spectrum disorder (ASD), this article delves into their underlying mechanisms, clinical presentations, diagnostic challenges, and therapeutic interventions. Highlighting the considerable disability and societal costs that these conditions impose, it reflects on the over six million individuals grappling with Alzheimer's, the 19 million American adults living with anxiety disorders, the three million with epilepsy, and the global reach of schizophrenia affecting approximately 20 million people. Furthermore, it examines the emerging landscape of ASD, noting the escalating diagnosis rates and the pressing need for innovative treatments and equitable healthcare access. Through a detailed exploration of current research, technological innovations, and the promise of personalized medicine, this review aims to illuminate the complexities of these conditions, advocate for early intervention strategies, and call for a unified approach to tackling the multifaceted challenges they present. The ultimate goal is to inform and inspire healthcare professionals, researchers, and policymakers to foster advancements that improve outcomes and quality of life for individuals affected by these profound neuropsychiatric disorders, steering towards a future where these conditions are no longer insurmountable.

Authors & Co-authors:  Grezenko Han H Rodoshi Zarin Nudar ZN Mimms Ciara S CS Ahmed Muhammad M Sabani Astrit A Hlaing May Su MS Batu Biniyam J BJ Hundesa Muhidin I MI Ayalew Biruk D BD Shehryar Abdullah A Rehman Abdur A Hassan Ahmad A

Study Outcome 

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Statistics
Citations :  2022 Alzheimer's disease facts and figures. The Alzheimer's Association. Alzheimers Dement. 18;18:700–789.
Authors :  12
Identifiers
Doi : e58776
SSN : 2168-8184
Study Population
Male,Female
Mesh Terms
Other Terms
autism spectrum disorder and anxiety disorder;clinical anxiety;depression;epilepsy;schizophrenia
Study Design
Study Approach
Country of Study
Publication Country
United States