Effects of mindfulness-based interventions on symptoms and interoception in trauma-related disorders and exposure to traumatic events: Systematic review and meta-analysis.
Journal: Psychiatry research
Volume: 336
Issue:
Year of Publication:
Affiliated Institutions:
University Department of Psychiatry, Academic Centre, College Keep, University of Southampton, UK; Southern Health National Health Service Foundation Trust, Southampton, UK; Department of Psychiatry, University of Milan, Department of Biomedical and Clinical Sciences "Luigi Sacco", ASST Fatebenefratelli-Sacco, Milan, Italy.
Center for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; Université Paris Nanterre, DysCo Lab, Nanterre F-, France; Université de Paris, Laboratoire de Psychopathologie et Processus de Santé, Boulogne-Billancourt F-, France.
University Department of Psychiatry, Academic Centre, College Keep, University of Southampton, UK; Southern Health National Health Service Foundation Trust, Southampton, UK.
Center for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
Department of Psychiatry, University of Milan, Department of Biomedical and Clinical Sciences "Luigi Sacco", ASST Fatebenefratelli-Sacco, Milan, Italy; Aldo Ravelli" Center for Neurotechnology and Brain Therapeutic, University of Milan, Milan , Italy.
Department of Psychiatry, University of Milan, Department of Biomedical and Clinical Sciences "Luigi Sacco", ASST Fatebenefratelli-Sacco, Milan, Italy; Aldo Ravelli" Center for Neurotechnology and Brain Therapeutic, University of Milan, Milan , Italy; Department of Psychiatry, Bipolar Disorders Clinic, Stanford Medical School, Stanford University, Stanford, CA, USA.
Center for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK; Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK; Solent National Health Service Trust, Southampton, UK; Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, New York, USA; DiMePRe-J-Department of Precision and Regenerative Medicine-Jonic Area, University "Aldo Moro", Bari, Italy.
University Department of Psychiatry, Academic Centre, College Keep, University of Southampton, UK; Southern Health National Health Service Foundation Trust, Southampton, UK; University Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
University Department of Psychiatry, Academic Centre, College Keep, University of Southampton, UK; Southern Health National Health Service Foundation Trust, Southampton, UK. Electronic address: N.Huneke@soton.ac.uk.
Abstract summary
Interoception is defined as the sense of the internal state of the body. Dysfunctions in interoception are found in several mental disorders, including trauma-related conditions. Mindfulness-Based Interventions (MBIs) have been shown to influence interoceptive processes. Randomised controlled trials (RCTs) have investigated whether MBIs impact symptoms and interoception in patients with trauma-related disorders. We undertook a systematic review and meta-analysis to synthesize these data. We included RCTs with an MBI arm which enrolled adult patients with trauma related-disorders or exposure to a traumatic experience, and addressed changes in interoception and trauma-related symptoms. A random-effects multivariate meta-analytic model was performed to quantify group differences in score change from baseline to follow-up. Twelve studies were included in the systematic review, and eleven in the meta-analysis. Overall, MBIs showed small to moderate positive effects on both interoception and symptoms. Despite a high heterogeneity in results, sensitivity analyses confirmed the robustness of the findings. We conclude that the efficacy of MBIs on trauma-related symptoms and interoception is supported by randomised evidence. However, further research is needed to understand whether changes in interoception might underpin the effectiveness of MBIs in trauma-related disorders.
Authors & Co-authors:
Molteni L L
Gosling C J CJ
Fagan H A HA
Hyde J J
Benatti B B
Dell'Osso B B
Cortese S S
Baldwin D S DS
Huneke N T M NTM
Study Outcome
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