Prevalence of Hypertension and Its Associated Risk Factors among 34,111 HAART Naïve HIV-Infected Adults in Dar es Salaam, Tanzania.

Journal: International journal of hypertension

Volume: 2016

Issue: 

Year of Publication: 

Affiliated Institutions:  Department of Physiology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. Management and Development for Health, HIV/AIDS Care and Treatment Program, Dar es Salaam, Tanzania; Africa Academy for Public Health, P.O. Box , Dar es Salaam, Tanzania. Management and Development for Health, HIV/AIDS Care and Treatment Program, Dar es Salaam, Tanzania. Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Biostatistics, Harvard TH Chan School of Public Health, Boston, MA, USA. Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Tufts University School of Medicine, Boston, MA, USA. Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA. Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA. Department of Psychiatry and Mental Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA; Department of Global Health and Population, Harvard TH Chan School of Public Health, Boston, MA, USA.

Abstract summary 

. Elevated blood pressure has been reported among treatment naïve HIV-infected patients. We investigated prevalence of hypertension and its associated risk factors in a HAART naïve HIV-infected population in Dar es Salaam, Tanzania. . A cross-sectional analysis was conducted among HAART naïve HIV-infected patients. Hypertension was defined as systolic blood pressure (SBP) ≥ 140 mmHg and/or diastolic blood pressure (DBP) ≥ 90 mmHg. Overweight and obesity were defined as body mass index (BMI) between 25.0-29.9 kg/m and ≥30 kg/m, respectively. We used relative risks to examine factors associated with hypertension. . Prevalence of hypertension was found to be 12.5%. After adjusting for possible confounders, risk of hypertension was 10% more in male than female patients. Patients aged ≥50 years had more than 2-fold increased risk for hypertension compared to 30-39-years-old patients. Overweight and obesity were associated with 51% and 94% increased risk for hypertension compared to normal weight patients. Low CD4+ T-cell count, advanced WHO clinical disease stage, and history of TB were associated with 10%, 42%, and 14% decreased risk for hypertension. . Older age, male gender, and overweight/obesity were associated with hypertension. Immune suppression and history of TB were associated with lower risk for hypertension. HIV treatment programs should screen and manage hypertension even in HAART naïve individuals.

Authors & Co-authors:  Njelekela Marina M Muhihi Alfa A Aveika Akum A Spiegelman Donna D Hawkins Claudia C Armstrong Catharina C Liu Enju E Okuma James J Chalamila Guerino G Kaaya Sylvia S Mugusi Ferdinand F Fawzi Wafaie W

Study Outcome 

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Citations :  Oguntibeju O. O. Quality of life of people living with HIV and AIDS and antiretroviral therapy. HIV/AIDS—Research and Palliative Care. 2012;4:117–124. doi: 10.2147/hiv.s32321.
Authors :  12
Identifiers
Doi : 5958382
SSN : 2090-0384
Study Population
Male,Female
Mesh Terms
Other Terms
Study Design
Cross Sectional Study
Study Approach
Country of Study
Tanzania
Publication Country
United States