The Interplay of Comorbidities in Chronic Heart Failure: Challenges and Solutions.

Journal: Current cardiology reviews

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Affiliated Institutions:  Government Medical College, Kadapa, India. CMH Lahore Medical College & Institute of Dentistry, Lahore, Pakistan. Universidad Central de Venezuela, Venezuela. West China Medical School, Sichuan University, Chengdu, China. Case Western Reserve University, Cleveland, OH, United States of America. Kasturba Medical College, Manipal, India. Government Medical College, Patiala, Punjab, India. Department of Internal Medicine, CMH Lahore Medical College & Institute of Dentistry, Lahore, Pakistan. Faculty of Medicine, University of Khartoum, Khartoum, Sudan. Department of Epidemiology and Public Health, Emory University Rollins School of Public Health, Atlanta, USA.

Abstract summary 

Chronic heart failure (HF) is frequently associated with various comorbidities. These comorbid conditions, such as anemia, diabetes mellitus, renal insufficiency, and sleep apnea, can significantly impact the prognosis of patients with HF.This review aims to synthesize current evidence on the prevalence, impact, and management of comorbidities in patients with chronic HF.A comprehensive review was conducted, with a rigorous selection process. Out of an initial pool of 59,030 articles identified across various research modalities, 134 articles were chosen for inclusion. The selection spanned various research methods, from randomized controlled trials to observational studies.Comorbidities are highly prevalent in patients with HF and contribute to increased hospitalization rates and mortality. Despite advances in therapies for HF with reduced ejection fraction, options for treating HF with preserved ejection fraction remain sparse. Existing treatment protocols often lack standardization, reflecting a limited understanding of the intricate relationships between HF and associated comorbidities.There is a pressing need for a multidisciplinary, tailored approach to manage HF and its intricate comorbidities. This review underscores the importance of ongoing research efforts to devise targeted treatment strategies for HF patients with various comorbid conditions.

Authors & Co-authors:  Agress Shashipriya S Sheikh Jannat S JS Perez Ramos Aida A AA Kashyap Durlav D Razmjouei Soha S Kumar Joy J Singh Mankaranvir M Lak Muhammad Ali MA Osman Ali A Zia Ul Haq Muhammad M

Study Outcome 

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Citations : 
Authors :  10
Identifiers
Doi : 10.2174/011573403X289572240206112303
SSN : 1875-6557
Study Population
Male,Female
Mesh Terms
Other Terms
Chronic heart failure;comorbidity management;multidisciplinary approach;preserved ejection fraction;reduced ejection fraction;treatment standardization.
Study Design
Randomized Control Trial
Study Approach
Country of Study
Publication Country
United Arab Emirates