invasive infection in a patient with Hirschsprung disease: A case report.
Volume: 71
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Abstract summary
is a ubiquitous aerobic, motile, gram-negative bacilli. The human gastro-intestinal tract is known to harbor this rarely opportunistic microorganism. We describe a rare case of invasive infection with a gastrointestinal starting point due to in a patient with Hirschsprung disease.It is about a newborn female who was admitted on the 3rd day of life to the neonatal intensive care unit for intestinal obstruction. On the 9th day of life, while managing the neonatal obstruction, the patient developed febrile peaks. Cytobacteriological examination of cerebrospinal fluid, blood cultures and culture of umbilical vein catheter allowed the exclusive isolation of . It was producing extended spectrum beta-lactamase and was treated with intravenous imipenem After favourable evolution, the patient was transferred to the pediatric surgery department. There, she was diagnosed with Hirschsprung disease.Knowledge of the route of transmission of is limited and the possible source of the infection is unclear. However, the authors describe three hypotheses of contamination of our propositus. In our patient, one or more of these routes of contamination would be possible. Indeed, bacteremia could occur as a result of a bacterial translocation across the mucosal barrier of the colon altered by Hirschsprung disease, antibiotic use and feeding practices.Infection with revealed a wide range of infection. It has only recently been acknowledged as an emerging pathogen. Further studies of the pathogenesis and risk factors are required.Study Outcome
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Citations : Lee B., Sir J.J., Park S.W., Kwak C.H., Kim S.M., Kim S.B. A case of Leclercia adecarboxylata endocarditis in a woman with endometrial cancer. Am J Med Sci [Internet] 2009;337(2):146–147. doi: 10.1097/MAJ.0b013e31817bf997. Available from:Authors : 10
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Doi : 102927SSN : 2049-0801