Does cannabis affect cognitive functioning in patients with schizophrenia?

Journal: Schizophrenia research. Cognition

Volume: 36

Issue: 

Year of Publication: 

Affiliated Institutions:  Laboratory of Clinical Neuroscience and Mental Health, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco. Legal medicine service University Hospital Center, Ibn Rochd, Casablanca, Morocco. University Psychiatric Center, Ibn Rochd, Casablanca, Morocco. Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, Morocco.

Abstract summary 

Cannabis use impairs cognitive performance in healthy subjects; several studies have shown improved cognitive outcomes in schizophrenic patients using cannabis. The aim of this study was to evaluate the effects of cannabis use on cognitive function in Moroccan patients with schizophrenia who were cannabis users.Two groups were recruited in a Moroccan University Psychiatric Centre. Fifty patients diagnosed with schizophrenia according to the DSM-V who were cannabis users (SZ CANN +) and forty-nine patients diagnosed with schizophrenia according to DSM-V who do not use cannabis (SZ CANN-). Cognitive functioning was assessed using the CogState neuropsychological battery.The results of the study suggest that SZ CANN- patients performed better in the test of psychomotor function, attention and verbal memory. While SZ CANN+ patients performed better in the test of working memory, visual memory and emotional recognition. We found no relationship between SZ CANN+ patients and SZ CANN- patients concerning executive function.Our results suggest that cannabis use may have different effects on neurocognitive functioning. It is associated with disorders of psychomotor function, attention and verbal memory. So, it is associated with an improvement in working memory, visual memory and emotion recognition.

Authors & Co-authors:  Rachid Hajar H Saif Zineb Z Raoui Salma S Serhier Zineb Z Agoub Mohamed M

Study Outcome 

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Statistics
Citations :  Andréasson S., Allebeck P., Engstrom A., Rydberg U. Cannabis and schizophrenia: a longitudinal study of Swedish conscripts. Lancet. 1987;2:1483–1486. doi: 10.1016/s0140-6736(87)92620-1.
Authors :  5
Identifiers
Doi : 100299
SSN : 2215-0013
Study Population
Male,Female
Mesh Terms
Other Terms
Battery cognitive;Cannabis;Cognitive performance;Psychiatric disorders;Schizophrenia
Study Design
Study Approach
Country of Study
Publication Country
United States