Proxy Responses for Mass Drug Administration Coverage Surveys: The Trends and Biases When Others are Allowed to Respond.

Journal: The American journal of tropical medicine and hygiene

Volume: 106

Issue: 1

Year of Publication: 2022

Affiliated Institutions:  Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, Pennsylvania. Direction de la Protection de la Santé de la Population, Ministère de la Santé, Ouagadougou, Burkina Faso. Vector Control Division, Ministry of Health, Kampala, Uganda. Lymphatic Filariasis Control Program, Ministry of Health and Population, Lilongwe, Malawi. Neglected Tropical Disease Support Center, Task Force for Global Health, Decatur, Georgia.

Abstract summary 

Coverage surveys for mass drug administration (MDA) rely on respondent recall and often permit proxy responses, whereby another household member is allowed to respond on behalf of an absent individual. In this secondary analysis of coverage surveys in Malawi, Burkina Faso, and Uganda, we explore the characteristics of individuals who require proxy responses and quantify the association between proxy responses and reported drug coverage. The adjusted logistic regression model found that men 11-39 years and women 11-18 years who were eligible for MDA had greater odds of requiring a proxy response compared with ineligible men and women in the same age groups. A hierarchical multivariable analysis found that proxy responses had 1.70 times the odds of reporting ingestion of MDA drugs compared with first-person responses, controlling for age and sex (95% CI: 1.17, 2.46). This finding is surprising, given that individuals absent during a coverage survey may also have been absent during the MDA, and suggests that proxy responses may be leading to an inflation of survey estimates of drug coverage. This study highlights the possibility for recall bias in proxy responses to MDA coverage; however, excluding absent individuals from coverage surveys would introduce a new bias. Further research is necessary to determine the best method for obtaining information on drug coverage when individuals are absent.

Authors & Co-authors:  Jose Rini R Bougma Roland R Drabo Franck F Tukahebwa Edridah Muheki EM Mkwanda Square S Gass Katherine K

Study Outcome 

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Statistics
Citations :  Ramaiah KD, Radhamani MP, John KR, Evans DB, Guyatt H, Joseph A, Datta M, Vanamail P, 2000. The impact of lymphatic filariasis on labour inputs in southern India: results of a multi-site study. Ann Trop Med Parasitol 94: 353–364.
Authors :  6
Identifiers
Doi : 10.4269/ajtmh.21-0817
SSN : 1476-1645
Study Population
Men,Women
Mesh Terms
Adolescent
Other Terms
Study Design
Cross Sectional Study
Study Approach
Country of Study
Uganda
Publication Country
United States