The benefits of care: treated HIV infection and health-related quality of life among older-aged people in Uganda.

Journal: Aging & mental health

Volume: 27

Issue: 9

Year of Publication: 

Affiliated Institutions:  Medical Practice Evaluation Center, Massachusetts General Hospital, MA, USA. Centre for Aging and Serious Illness, Massachusetts General Hospital, MA, USA. Department of Medicine, Harvard Medical School, Harvard University, MA, USA. Missouri Institute of Mental Health University of Missouri - St Louis, MO, USA. Department of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK. Faculty of Medicine, Mbarara University of Science and Technology in Mbarara, Uganda. Department of Psychiatry, the College of Health Sciences, Makerere University, Uganda. Department of Health Sciences, Northeastern University, MA, USA. Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, USA. Department of Medicine, University of California, San Francisco, USA. Global Health Collaborative, Mbarara University of Science and Technology, Mbarara, Uganda.

Abstract summary 

The objective of this study is to explore how HIV care affects health-related quality of life (HRQoL) among older people in Uganda.We enrolled older-aged (≥49 years) people with HIV receiving HIV care and treatment, along with age- and sex-similar people without HIV. We measured health-related quality of life using the EQ-5D-3L scale.People with HIV ( = 298) and people without HIV ( = 302) were similar in median age (58.4 vs. 58.5 years), gender, and number of comorbidities. People with HIV had higher self-reported health status ( = 7.0; 95% confidence interval [CI], 4.2-9.7), higher EQ-5D utility index ( = 0.05; 95% CI, 0.02-0.07), and were more likely to report no problems with self-care (adjusted odds ratio [AOR], 2.0; 95% CI, 1.2-3.3) or pain/discomfort (AOR = 1.8, 95% CI, 1.3-2.8). Relationships between HIV serostatus and health-related quality of life differed by gender, but not age.Older people with HIV receiving care and treatment reported higher health-related quality of life than people without HIV in Uganda. Access to primary care through HIV programs and/or social network mobilization may explain this difference, but further research is needed to elucidate the mechanisms.

Authors & Co-authors:  Quach Lien T LT Ritchie Christine S CS Tsai Alexander C AC Reynolds Zahra Z Paul Robert R Seeley Janet J Tong Yao Y Hoeppner Susanne S Okello Samson S Nakasujja Noeline N Olivieri-Mui Brianne B Saylor Deanna D Greene Meredith M Asiimwe Stephen S Siedner Mark J MJ

Study Outcome 

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Statistics
Citations :  Bhatia R, Ryscavage P, & Taiwo B (2012). Accelerated aging and human immunodeficiency virus infection: Emerging challenges of growing older in the era of successful antiretroviral therapy. Journal of Neurovirology, 18(4), 247–255. 10.1007/s13365-011-0073-y
Authors :  15
Identifiers
Doi : 10.1080/13607863.2022.2150143
SSN : 1364-6915
Study Population
Male,Female
Mesh Terms
Other Terms
HIV;Uganda;anxiety and trauma related disorders;depression ;  mood disorders;epidemiology (mental health);health service use;health-related quality of life;older people;quality of life/wellbeing;  psychosocial and cultural aspects
Study Design
Cross Sectional Study
Study Approach
Country of Study
Uganda
Publication Country
England