Dose-Response Relationship between Endurance Training Prescription Variables and Increases in Aerobic Performance of Healthy and Unhealthy Middle and Very Old Individuals Aged 70 Years and Older: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Journal: Life (Basel, Switzerland)

Volume: 11

Issue: 2

Year of Publication: 

Affiliated Institutions:  High Institute of Sport and Education of Sfax, Sfax , Tunisia. Laboratory for Industrial and Applied Mathematics (LIAM), Department of Mathematics and Statistics, York University, Toronto, ON MJ P, Canada. College of Psychology and Sociology, Exercise and Mental Health Laboratory, Shenzhen University, Shenzhen , China. Institute of Kinesiology Research, Science and Research Centre, SI- Koper, Slovenia. Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), Section of Psychiatry, Genoa University, Genoa, Italy. High Institute of Applied Biology of Médenine, Medenine , Tunisia.

Abstract summary 

The objectives of this systematic review and meta-analysis were to quantify the effectiveness of endurance training (ET) on aerobic performance (i.e., peak oxygen uptake (VO)) in healthy and unhealthy middle and very old adults aged 70 years and older, and to provide dose-response relationships of training prescription variables (in terms of frequency, and volume).Several scholarly databases (i.e., PubMed/MEDLINE, SpringerLink, ScienceDirect Journals, and Taylor & Francis Online-Journals) were searched, identifying randomized controlled studies that investigated the effectiveness of ET on VO in older adults. Standardized mean differences (SMD) were calculated.In terms of changes differences between experimental and control group, ET produced significant large effects on VO performance (SMD = 2.64 (95%CI 0.97-4.31)). The moderator analysis revealed that "health status" variable moderated ET effect onVO performance. More specifically, ET produced larger SMD magnitudes on VO performance in healthy compared with unhealthy individuals. With regard to the dose-response relationships, findings from the meta-regression showed that none of the included training prescription variables predicted ET effects on VO performance.ET is an effective mean for improving aerobic performance in healthy older adults when compared with their unhealthy counterparts.

Authors & Co-authors:  Cheour Sarah S Cheour Chouaib C Bragazzi Nicola Luigi NL Zou Liye L Paravlic Armin H AH Slimani Maamer M Cheour Foued F

Study Outcome 

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Statistics
Citations :  Watad A., Bragazzi N.L., Adawi M., Amital H., Toubi E., Porat B.-S., Shoenfeld Y. Autoimmunity in the elderly: Insights from basic science and clinics—A mini-review. Gerontology. 2017;63:515–523. doi: 10.1159/000478012.
Authors :  7
Identifiers
Doi : 121
SSN : 2075-1729
Study Population
Male,Female
Mesh Terms
Other Terms
dose–response relationship;elderly;exercise;physical activity training prescriptions;physical endurance;physical fitness;systematic review and meta-analysis
Study Design
Randomized Control Trial,Case Control Trial,Cross Sectional Study
Study Approach
Systemic Review
Country of Study
Publication Country
Switzerland