Quality of Life, Fatigue, and Physical Symptoms Post-COVID-19 Condition: A Cross-Sectional Comparative Study.

Journal: Healthcare (Basel, Switzerland)

Volume: 11

Issue: 11

Year of Publication: 

Affiliated Institutions:  Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh , Saudi Arabia. General Administration of School Health, Ministry of Health, Riyadh , Saudi Arabia. Department of Medicine, Gastroenterology Division, College of Medicine, King Saud University, Riyadh , Saudi Arabia. Department of Medicine, Pulmonary Division, College of Medicine, King Saud University, Riyadh , Saudi Arabia. High Institute of Sport and Physical Education of Sfax, University of Sfax, Sfax , Tunisia. Government Hospitals, Manama , Bahrain. Department of Medicine, College of Medicine, University Sleep Disorders Center, King Saud University, Riyadh , Saudi Arabia.

Abstract summary 

The magnitude of post-COVID-19 syndrome was not thoroughly investigated. This study evaluated the quality of life and persistence of fatigue and physical symptoms of individuals post-COVID-19 compared with noninfected controls. The study included 965 participants; 400 had previous COVID-19 disease and 565 controls without COVID-19. The questionnaire collected data on comorbidities, COVID-19 vaccination, general health questions, and physical symptoms, in addition to validated measures of quality of life (SF-36 scale), fatigue (fatigue severity scale, FSS), and dyspnea grade. COVID-19 participants complained more frequently of weakness, muscle pain, respiratory symptoms, voice disorders, imbalance, taste and smell loss, and menstrual problems compared to the controls. Joint symptoms, tingling, numbness, hypo/hypertension, sexual dysfunction, headache, bowel, urinary, cardiac, and visual symptoms did not differ between groups. Dyspnea grade II-IV did not differ significantly between groups ( = 0.116). COVID-19 patients scored lower on the SF-36 domains of role physical ( = 0.045), vitality ( < 0.001), reported health changes ( < 0.001), and mental-components summary ( = 0.014). FSS scores were significantly higher in COVID-19 participants (3 (1.8-4.3) vs. 2.6 (1.4-4); < 0.001). COVID-19 effects could persist beyond the acute infection phase. These effects include changes in quality of life, fatigue, and persistence of physical symptoms.

Authors & Co-authors:  AlRasheed Maha M MM Al-Aqeel Sinaa S Aboheimed Ghada I GI AlRasheed Noura M NM Abanmy Norah Othman NO Alhamid Ghadeer Abdulaziz GA Alnemari Hadeel Mohammed HM Alkhowaiter Saad S Alharbi Abdullah Rashed AR Khurshid Fowad F Trabelsi Khaled K Jahrami Haitham A HA BaHammam Ahmed S AS

Study Outcome 

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Statistics
Citations :  Fernández-de-Las-Peñas C. Long COVID: Current definition. Infection. 2022;50:285–286. doi: 10.1007/s15010-021-01696-5.
Authors :  13
Identifiers
Doi : 1660
SSN : 2227-9032
Study Population
Male,Female
Mesh Terms
Other Terms
SF-36;fatigue;fatigue severity scale;post-acute COVID-19 syndrome;quality of life
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
Switzerland