The association between psychopathology and substance use: adolescent and young adult substance users in inpatient treatment in Cape Town, South Africa.

Journal: The Pan African medical journal

Volume: 17 Suppl 1

Issue: Suppl 1

Year of Publication: 2014

Affiliated Institutions:  Adolescent Health and Research Unit, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa ; School of Public Health and Family Medicine, University of Cape Town, South Africa. Adolescent Health and Research Unit, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa ; Deceased. Biostatistics Unit, Medical Research Council, Cape Town, South Africa. School of Public Health and Family Medicine, University of Cape Town, South Africa. Alcohol and Drug Abuse Research Unit, Medical Research Council, Pretoria, South Africa.

Abstract summary 

Evidence suggests that comorbid psychopathology can negatively affect treatment outcomes in substance users. In South Africa, limited information exists regarding the prevalence, nature and role of psychiatric comorbidity in substance users. This study examined psychiatric comorbidity and its association with specific substance use, and young adult substance users in treatment for substance use.Male and female inpatient substance users (n=95; ages 17-30 years) were sampled consecutively in order of admission from three clinics in Cape Town. An interview schedule was administered to elicit patients' sociodemographic and substance use history details. The computer-assisted Diagnostic Interview Schedule DSM IV (C-DIS IV) was administered to screen patients for current psychiatric disorders.The sample was largely male, Coloured, Muslim and single. Cannabis (51.6%) and crystal methamphetamine (17.9%) were the most common first substances of use. Heroin (53.7%) and crystal methamphetamine (33.7%) were the most common substances for which treatment was sought (primary substances). The most common comorbid psychopathologies were anti-social personality disorder (ASPD 87.4%) and conduct disorder (CD 67.4%). Regression analyses showed a marginally significant association between specific phobia and first use of cannabis, but indicated no statistically significant associations between psychopathology and substance use.The results demonstrated a high proportion of previously unidentified comorbid psychopathology in inpatient substance users. Further research is needed to investigate psychiatric comorbidity in inpatient substance users.

Authors & Co-authors:  Saban Amina A Flisher Alan A Laubscher Ria R London Leslie L Morojele Neo N

Study Outcome 

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Citations :  Volkow N. Drug abuse and mental illness: progress in understanding comorbidity. Am J Psychiatry. 2001;158(8):1181–1183.
Authors :  5
Identifiers
Doi : 8
SSN : 1937-8688
Study Population
Female
Mesh Terms
Adolescent
Other Terms
Comorbidity;psychopathology;substance use treatment
Study Design
Cross Sectional Study
Study Approach
Country of Study
South Africa
Publication Country
Uganda