Depressive symptoms and substance use as mediators of stigma affecting men who have sex with men in Lesotho: a structural equation modeling approach.

Journal: Annals of epidemiology

Volume: 26

Issue: 8

Year of Publication: 2018

Affiliated Institutions:  Department of Epidemiology, Center for Public Health and Human Rights, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Electronic address: wda@jhu.edu. Department of Epidemiology, Center for Public Health and Human Rights, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD. Population Services International, Johannesburg, South Africa. Ministry of Health, Maseru, Lesotho. Matrix Support Group, Maseru, Lesotho.

Abstract summary 

Research on the relationship between sexual orientation-related stigma and risks for HIV among men who have sex with men (MSM) is limited. This study tests a hypothesis that substance use and depressive symptoms mediate the relationship between stigma in the health care system and HIV-related risk practices among MSM in Maseru, Lesotho.In 2014, we conducted a cross-sectional study among MSM in Lesotho accrued via respondent-driven sampling including a survey and biological testing for HIV. The hypothesis was tested using structural equation modeling.Of the 318 participants, 22.3% had experienced stigma in the health care system. Stigma in the health care system was associated with depression (β = 0.329, P = .018) and alcohol use (β = 1.417, P = .001). Noninjection illicit drug use (β = 0.837, P = .039) and alcohol use (β = 0.282, P = .000) significantly predicted number of sex partners. Stigma was directly associated with condomless anal sex (β = 0.441, P = .036), and no indirect association was found.Alcohol use and depressive symptoms mediate the relationship between MSM stigma in the health care system and reported number of sex partners. The implications are significant with a focus on the need for comprehensive interventions addressing stigma and mental health when aiming to improve more proximal HIV-related risk practices for MSM.

Authors & Co-authors:  Wendi Da D Stahlman Shauna S Grosso Ashley A Sweitzer Stephanie S Ketende Sosthenes S Taruberekera Noah N Nkonyana John J Mothopeng Tampose T Baral Stefan S

Study Outcome 

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Citations : 
Authors :  9
Identifiers
Doi : 10.1016/j.annepidem.2016.06.005
SSN : 1873-2585
Study Population
Men
Mesh Terms
Adult
Other Terms
Depressive symptoms;HIV-related risk practices;MSM;SEM;Stigma;Substance use
Study Design
Cross Sectional Study
Study Approach
Country of Study
Lesotho
Publication Country
United States