Migrant status and identification as ultra-high risk for psychosis and transitioning to a psychotic disorder.

Journal: Acta psychiatrica Scandinavica

Volume: 141

Issue: 1

Year of Publication: 2021

Affiliated Institutions:  Orygen, The National Centre of Excellence in Youth Mental Health, Parkville, Vic., Australia.

Abstract summary 

Certain migrant groups are more likely to develop a psychotic disorder compared to the native-born populations, and a younger age at migration is associated with greater risk. However, it is not known at which stage migration has an effect on the development of psychotic disorders. We examined whether migrants were more likely to be identified as ultra-high risk for psychosis (UHR) compared to native-born young people and whether migrant status was associated with the risk of transition to a full-threshold psychotic disorder.The cohort included all young people aged 15-24 who were identified as UHR at a specialist clinic over a five-year period (2012-16). Australian census data were used to obtain the at-risk population. Poisson regression was used to calculate rate ratios and Cox regression analysis determined hazard ratios.467 young people were identified as UHR, of which 13.5% (n = 63) were born overseas. First-generation migrants were 2.6-fold less likely to be identified as UHR compared to Australian-born young people (IRR = 0.39, 95% CI [0.30, 0.51], P < 0.001). There was no difference between migrant and native-born young people in their risk of transitioning to a psychotic disorder (HR = 0.90, 95% CI [0.39, 2.08], P = 0.81).UHR first-generation migrants may be under-accessing mental health services.

Authors & Co-authors:  Geros H H Sizer H H Mifsud N N Reynolds S S Kim D J DJ Eaton S S McGorry P P Nelson B B O'Donoghue B B

Study Outcome 

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Statistics
Citations :  Cantor-Graae E, Selten J-P. Schizophrenia and migration: a meta-analysis and review. Am J Psychiatry 2005;162:12-24.
Authors :  9
Identifiers
Doi : 10.1111/acps.13099
SSN : 1600-0447
Study Population
Male,Female
Mesh Terms
Adolescent
Other Terms
UHR;incidence;migrants;risk;ultra-high risk for psychosis
Study Design
Cohort Study,Cross Sectional Study
Study Approach
Country of Study
Publication Country
United States