A prospective observational study of heroin users in Johannesburg, South Africa: Assessing psychiatric comorbidities and treatment outcomes.

Journal: Comprehensive psychiatry

Volume: 95

Issue: 

Year of Publication: 2020

Affiliated Institutions:  Department of Psychiatry, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, York Road, Parktown, Johannesburg, , South Africa. Electronic address: nirvana.morgan@wits.ac.za. School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Department of Psychiatry, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Abstract summary 

Despite the rise in heroin use in sub Saharan-Africa opioid agonist maintenance treatment (OAMT) is still not state-funded in South Africa and many other African countries. In South Africa there has been little data published on the profile of heroin users and the outcomes of treatment for those who attend public treatment services.300 heroin users from two state-funded rehabilitation centres in Johannesburg were studied at entry into rehabilitation and 3-months after treatment. Treatment consisted of inpatient detoxification and inpatient psychosocial rehabilitation. Structured interviews measured changes in drug use, psychopathology and criminality post rehabilitation.Most (65.7%) smoked heroin in combination with cannabis while 29.7% were injecting users. Almost half the sample (49.3%) had at least one mental illness. Of the 252 (84%) participants seen at 3-month follow-up, 6.3% were abstinent of all substances (excluding tobacco), 65.5% had continued heroin use (CHU) and the balance used other substances. At follow-up there were significant decreases in heroin use (p<0.0001) and criminality (p<0.0001). There were however significant increases in alcohol use (p<0.0001), crystalmetamphetamine use (p=0.032) and the prevalence of current episode of major depression (p<0.0001). Just 11.9% received formal psychosocial treatment after leaving rehabilitation. None were on OAMT and only three participants were on psychotropic medication. None were tested for Hepatitis C during the study period and the majority (53%) did not know their HIV status.There are significant gaps in current treatment services for heroin users in South Africa. Retention in treatment and assessment and management of psychiatric and non-psychiatric comorbidities is low. Services need to be more integrated and should also include the provision of OAMT.

Authors & Co-authors:  Morgan Nirvana N Daniels William W Subramaney Ugasvaree U

Study Outcome 

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Citations : 
Authors :  3
Identifiers
Doi : 10.1016/j.comppsych.2019.152137
SSN : 1532-8384
Study Population
Male,Female
Mesh Terms
Adult
Other Terms
Comorbidities;Heroin;Heroin dependence;Nyaope;Treatment outcomes
Study Design
Cross Sectional Study
Study Approach
Country of Study
South Africa
Publication Country
United States