Development of a Natural Product Rich in Bioavailable Omega-3 DHA from Locally Available Ingredients for Prevention of Nutrition Related Mental Illnesses.

Journal: Journal of the American College of Nutrition

Volume: 39

Issue: 8

Year of Publication: 2021

Affiliated Institutions:  School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, Arusha, Tanzania. College of Science, Engineering and Technology, University of South Africa (UNISA), Pretoria, South Africa.

Abstract summary 

Poor mental health remains a serious public concern worldwide. The most vulnerable individuals are children and adolescents in developing countries. Nutritional deficiency of long-chain omega-3 fatty acids, particularly docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), have long been recognized as a major contributing factor for mental health illnesses. Provision of ready-to-use natural product rich in preformed Omega-3 DHA and EPA could address this problem. However, most commonly used products are expensive and contain less or no preformed Omega-3 DHA and EPA, making them less suitable for prevention of mental illnesses in resource-poor countries. The main objective of this study was to develop a natural product rich in preformed Omega-3 DHA and EPA from locally available ingredients. Linear programing (LP) was used to formulate a natural product rich in preformed Omega-3 DHA and other essential nutrients using locally available ingredients other than fish and dairy products. Laboratory analysis was then performed to validate the nutritional value of the LP-formulation using standard analytical methods. The relative difference between the LP tool calculated values, and the laboratory-analyzed values were calculated. Sensory testing was also done to evaluate consumer acceptance of the final product. Optimal formulation contained about 220 mg of preformed Omega-3 DHA + EPA, enough to meet the RDI for children aged 2-10 years. The LP analysis further showed that the cost of the developed product is USD 0.15/100 g, which is 50% lower than that of Plumpy'nut. Laboratory analysis revealed similar results as that of LP at P = 0.05. These findings indicate that ready-to-use natural food rich in preformed DHA and EPA can be developed from locally available ingredients.

Authors & Co-authors:  Charles Christina N CN Swai Hulda H Msagati Titus T Chacha Musa M

Study Outcome 

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Statistics
Citations : 
Authors :  4
Identifiers
Doi : 10.1080/07315724.2020.1727381
SSN : 1541-1087
Study Population
Male,Female
Mesh Terms
Cucurbita
Other Terms
linear programing;locally available ingredients;microalgae;nutrition related mental health;preformed omega-3 DHA
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
United States