ImPlementation REsearCh to DEvelop Interventions for People Living with HIV (the PRECluDE consortium): Combatting chronic disease comorbidities in HIV populations through implementation research.

Journal: Progress in cardiovascular diseases

Volume: 63

Issue: 2

Year of Publication: 2020

Affiliated Institutions:  Health Scientist Administrator and AAAS Science and Technology Policy Fellow, Implementation Science Branch (ISB), Center for Translation Research and Implementation Science (CTRIS), National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), U.S. Department of Health and Human Services, Bethesda, MD , United States of America; Office of Science Policy (OSP), Office of the Director (OD), National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD , United States of America. Electronic address: joyonna.gamble-george@nih.gov. Department of Medicine, Case Western Reserve University School of Medicine, University Hospitals Harrington Heart and Vascular Institute, Cleveland, OH , United States of America. Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH , United States of America. Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington School of Medicine, Seattle, WA , United States of America; Seattle-Denver Center of Innovation (COIN) for Veteran-Centered and Value-Driven Care, Veterans Affairs (VA) Puget Sound Health Care System, Seattle, WA , United States of America. Department of Medicine, Division of General Internal Medicine and Health Services Research (GIM and HSR), David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA , United States of America; GIM and HSR, Olive View-UCLA Medical Center Sylmar, Los Angeles, CA , United States of America; Community Engagement and Research Program, UCLA Clinical and Translational Science Institute, Los Angeles, CA , United States of America. Department of Medicine, Duke University School of Medicine, Durham, NC , United States of America; Department of Population Health Sciences, Duke University School of Medicine, Durham, NC , United States of America; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC , United States of America. Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington School of Medicine, Seattle, WA , United States of America; Pulmonary and Critical Care Section, VA Puget Sound Health Care System, Seattle, WA , United States of America. Department of Medicine, GIM and HSR, David Geffen School of Medicine, UCLA, Los Angeles, CA , United States of America; Department of Health Policy and Management, UCLA Fielding School of Public Health, Los Angeles, CA , United States of America. Department of Family Medicine, University of Rochester Medical Center, Rochester, NY , United States of America; Department of Public Health Sciences, University of Rochester Medical Center, Rochester, NY , United States of America; Center for Community Health and Prevention, University of Rochester Medical Center, Rochester, NY , United States of America; Center for Communication and Disparities Research, University of Rochester Medical Center, Rochester, NY , United States of America; Greater Rochester Practice-Based Research Network, Clinical and Translational Science Institute (CTSI), University of Rochester Medical Center, Rochester, NY , United States of America. Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA Jane and Terry Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA , United States of America; VA Health Services Research and Development (HSR&D) Service, Center for the Study of Healthcare Innovation, Implementation, and Policy (CSHIIP), VA Greater Los Angeles Healthcare System, North Hills, CA , United States of America. Department of Health Services, School of Public Health, University of Washington, Seattle, WA , United States of America; Health Services Research and Development, Seattle-Denver Center of Innovation for Veteran-Centered and Value-Driven Care, Veterans Administration (VA) Puget Sound Health Care System, Seattle, WA , United States of America. Department of Medicine, GIM and HSR, David Geffen School of Medicine, UCLA, Los Angeles, CA , United States of America; Department of Population Health, New York University (NYU) Grossman School of Medicine, New York, NY , United States of America. HIV Clinical Services, Parkland Health and Hospital System, Dallas, TX , United States of America; Department of Internal Medicine, University of Texas (UT) Southwestern Medical Center, Dallas, TX , United States of America. Clinical Directors Network, Inc. (CDN), New York, NY ; Community-Engaged Research, The Rockefeller University Center for Clinical and Translational Science, New York, NY , United States of America. Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, UCLA Jane and Terry Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA , United States of America; Sexual Health Programs, UCLA Jane and Terry Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA , United States of America; The Center for Culture, Trauma, and Mental Health Disparities, UCLA Jane and Terry Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA , United States of America; University of Cape Town, Rondebosch, Cape Town , South Africa.

Abstract summary 

Antiretroviral therapy (ART) prevented premature mortality and improved the quality of life among people living with the human immunodeficiency virus (PLWH), such that now more than half of PLWH in the United States are 50 years of age and older. Increased longevity among PLWH has resulted in a significant rise in chronic, comorbid diseases. However, the implementation of guideline-based interventions for preventing, treating, and managing such age-related, chronic conditions among the HIV population is lacking. The PRECluDE consortium supported by the Center for Translation Research and Implementation Science at the National Heart, Lung, and Blood Institute catalyzes implementation research on proven-effective interventions for co-occurring heart, lung, blood, and sleep diseases and conditions among PLWH. These collaborative research studies use novel implementation frameworks with HIV, mental health, cardiovascular, and pulmonary care to advance comprehensive HIV and chronic disease healthcare in a variety of settings and among diverse populations.

Authors & Co-authors:  Gamble-George Joyonna Carrie JC Longenecker Christopher T CT Webel Allison R AR Au David H DH Brown Arleen F AF Bosworth Hayden H Crothers Kristina K Cunningham William E WE Fiscella Kevin A KA Hamilton Alison B AB Helfrich Christian D CD Ladapo Joseph A JA Luque Amneris A Tobin Jonathan N JN Wyatt Gail E GE

Study Outcome 

Source Link: Visit source

Statistics
Citations :  Centers for Disease Control and Prevention. Estimated HIV incidence and prevalence in the United States, 2010–2016. HIV Surveillance Supplemental Report; 24 http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html, February 2019. (accessed 23 December 2019).
Authors :  16
Identifiers
Doi : 10.1016/j.pcad.2020.03.006
SSN : 1873-1740
Study Population
Male,Female
Mesh Terms
Adolescent
Other Terms
Antiretroviral therapy;COPD;Cardiovascular disease;Comorbidities;HIV;Implementation science
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
United States