Acceptability, Feasibility, and Preliminary Efficacy of a Resilience-Oriented Family Intervention to Prevent Adolescent HIV and Depression: A Pilot Randomized Controlled Trial.

Journal: AIDS education and prevention : official publication of the International Society for AIDS Education

Volume: 32

Issue: 1

Year of Publication: 2020

Affiliated Institutions:  Brown University School of Public Health, Providence, Rhode Island. Health Systems Research Unit, South African Medical Research Council, Tygerberg, South Africa. University of North Carolina at Chapel Hill, Gillings School of Global Public Health. Desmond Tutu HIV Foundation, Cape Town, South Africa. Judge Baker Children's Center, Harvard Medical School, and Boston Children's Hospital, Boston, Massachusetts. University of Cape Town. South African Medical Research Council Unit on Risk & Resilience in Mental Disorders, University of Cape Town. Alpert Medical School of Brown University, Providence, Rhode Island, and the Providence/Boston Center for AIDS Research.

Abstract summary 

We tested the acceptability, feasibility, and preliminary efficacy of Our Family Our Future, a resilience-oriented intervention engaging families in prevention of adolescent HIV and depression. South African adolescents, 13-15 years of age, with mild depressive symptoms, were randomized to intervention or wait-list using parallel assignment in a single-blind trial. HIV risk behavior and depression were evaluated at baseline, 1, and 3 months. We examined intervention satisfaction, fidelity, trial retention, and preliminary efficacy. One hundred-ninety-six adolescent-parent dyads completed eligibility screening and baseline, and n = 73 dyads were randomized. All families ranked intervention quality as good or excellent. Over 90% were satisfied with content. Facilitators were adherent to intervention protocol. All families were retained in post-intervention assessments. Intervention recipients reported diminished depressive symptoms, inconsistent condom use, and sexual activity, as well as increased HIV testing. Our Family Our Future is highly acceptable and feasible and should be tested in a future efficacy trial.

Authors & Co-authors:  Kuo Caroline C Mathews Catherine C Giovenco Danielle D Atujuna Millicent M Beardslee William W Hoare Jacqueline J Stein Dan J DJ Brown Larry K LK

Study Outcome 

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Statistics
Citations :  Angold A, Costello E, & Worthman C (1998). Puberty and depression: the roles of age, pubertal status and pubertal timing. Psychological Medicine, 28(1), 51–61.
Authors :  8
Identifiers
Doi : 10.1521/aeap.2020.32.1.67
SSN : 1943-2755
Study Population
Male,Female
Mesh Terms
Adolescent
Other Terms
South Africa;depression;family intervention;prevention;resilience
Study Design
Randomized Control Trial,Cross Sectional Study
Study Approach
Country of Study
South Africa
Publication Country
United States