Clinical advances in obsessive-compulsive disorder: a position statement by the International College of Obsessive-Compulsive Spectrum Disorders.

Journal: International clinical psychopharmacology

Volume: 35

Issue: 4

Year of Publication: 2021

Affiliated Institutions:  University of Hertfordshire, Hatfield. Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York, USA. Istituto di Neuroscienze, University of Florence, Firenze, Italy. Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich. University of Milan, Department of Biomedical and Clinical Sciences Luigi Sacco, Ospedale Sacco-Polo Universitario, ASST Fatebenefratelli-Sacco, Milan, Italy. Department of Medicine, Surgery and Health Sciences, UCO Clinica Psichiatrica, University of Trieste, Trieste, Italy. Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA. Western Sydney Obsessive-Compulsive and Related Disorders Service, Western Sydney Local Health District, Blacktown Hospital, Blacktown, New South Wales. OCD Clinic, Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bengaluru, India. OCD Spectrum Disorders Program, Institute and Department of Psychiatry, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo-SP, Brazil. Consultant Psychiatrist, SW London and St George's NHS Trust and St George's, University of London, London. Hertfordshire Partnership University NHS Foundation Trust, Welwyn Garden City, Hertfordshire. Department of Psychiatry, University of Cambridge, Cambridge. Department of Psychiatry and Behavioural Sciences, Stanford University, California, USA. St. Vincent's Hospital Melbourne and The University of Melbourne, Melbourne, Australia. Department of Psychiatry and Behavioural Neurosciences, McMaster University. SA MRC Unit on Risk and Resilience in Mental Disorders, Department of Psychiatry and Neuroscience Institute, University of Cape Town, Cape Town, South Africa. The Post Trauma Center, Chaim Sheba Medical Center, Ramat Gan. Department of Psychiatry, Bellvitge University Hospital-IDIBELL, University of Barcelona, Cibersam, Barcelona, Spain.

Abstract summary 

In this position statement, developed by The International College of Obsessive-Compulsive Spectrum Disorders, a group of international experts responds to recent developments in the evidence-based management of obsessive-compulsive disorder (OCD). The article presents those selected therapeutic advances judged to be of utmost relevance to the treatment of OCD, based on new and emerging evidence from clinical and translational science. Areas covered include refinement in the methods of clinical assessment, the importance of early intervention based on new staging models and the need to provide sustained well-being involving effective relapse prevention. The relative benefits of psychological, pharmacological and somatic treatments are reviewed and novel treatment strategies for difficult to treat OCD, including neurostimulation, as well as new areas for research such as problematic internet use, novel digital interventions, immunological therapies, pharmacogenetics and novel forms of psychotherapy are discussed.

Authors & Co-authors:  Fineberg Naomi A NA Hollander Eric E Pallanti Stefano S Walitza Susanne S Grünblatt Edna E Dell'Osso Bernardo Maria BM Albert Umberto U Geller Daniel A DA Brakoulias Vlasios V Janardhan Reddy Y C YC Arumugham Shyam Sundar SS Shavitt Roseli G RG Drummond Lynne L Grancini Benedetta B De Carlo Vera V Cinosi Eduardo E Chamberlain Samuel R SR Ioannidis Konstantinos K Rodriguez Carolyn I CI Garg Kabir K Castle David D Van Ameringen Michael M Stein Dan J DJ Carmi Lior L Zohar Joseph J Menchon Jose M JM

Study Outcome 

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Statistics
Citations :  Abdolhosseinzadeh S, Alizadeh N, Shams J, Asadi S, Ahmadiani A. BDNF association study with obsessive-compulsive disorder, its clinical characteristics, and response to fluvoxamine-treatment in Iranian patients. 2019a; 28:216–224
Authors :  26
Identifiers
Doi : 10.1097/YIC.0000000000000314
SSN : 1473-5857
Study Population
Male,Female
Mesh Terms
Evidence-Based Medicine
Other Terms
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
England