Screening for HIV-Associated Neurocognitive Disorders: Sensitivity and Specificity.

Journal: Current topics in behavioral neurosciences

Volume: 50

Issue: 

Year of Publication: 2021

Affiliated Institutions:  HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University Medical Center, New York, NY, USA. rnr@cumc.columbia.edu. Department of Psychology, Fordham University, The Bronx, NY, USA. Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa. HIV Neurobehavioral Research Program, Center for Medicinal Cannabis Research, University of California, San Diego, San Diego, CA, USA. Centre for Urban Health Solutions, St Michael's Hospital, Toronto University, Toronto, ON, Canada.

Abstract summary 

HIV-associated neurocognitive disorder (HAND) remains prevalent among people living with HIV (PLWH), especially the mild forms, even those with well-controlled HIV. Recommendations from the literature suggest routine and regular screening for HAND to detect it early and manage it effectively and adjust treatments, if warranted, when present. However, screening for HAND is not routinely done, as there are no current guidelines on when to screen and which test or tests to use. Furthermore, many of the available screening tools for HAND often cannot accurately detect the mild forms of HAND and require highly trained healthcare professionals to administer and score the tests, a requirement that is not feasible for those low- and middle-income countries with the highest HIV incidence and prevalence rates. The purpose of this chapter was to review recent research on screening tests to detect HAND and report on the strengths, limitations, and psychometric properties of those tests to detect HAND.

Authors & Co-authors:  Robbins Reuben N RN Scott Travis M TM Gouse Hetta H Marcotte Thomas D TD Rourke Sean B SB

Study Outcome 

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Statistics
Citations :  Anderson AM, Lennox JL, Nguyen ML, Waldrop-Valverde D, Tyor WR, Loring DW (2016) Preliminary study of a novel cognitive assessment device for the evaluation of HIV-associated neurocognitive impairment. J Neurovirol 22(6):816–822
Authors :  5
Identifiers
Doi : 10.1007/7854_2019_117
SSN : 1866-3370
Study Population
Male,Female
Mesh Terms
AIDS Dementia Complex
Other Terms
HAND;HIV;Neurocognitive impairment;Psychometrics;Screening;Test
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
Germany