Increase in HIV incidence in women exposed to rape.

Journal: AIDS (London, England)

Volume: 35

Issue: 4

Year of Publication: 2021

Affiliated Institutions:  Gender and Health Research Unit, South African Medical Research Council. Biostatistics Unit, South African Medical Research Council, Cape Town. Anxiety and Stress Disorder Unit, University of Stellenbosch, Stellenbosch. Non-Communicable Diseases Research Unit, South African Medical Research Council. Alcohol, Tobacco and Other Drug Research Unit, South African Medical Research Council. Department of Sexual and Reproductive Health and Research, World Health Organization (WHO), Geneva, Switzerland.

Abstract summary 

To determine the incidence of HIV acquisition in women postrape compared with a cohort of women who had not been raped.A prospective cohort study.The Rape Impact Cohort Evaluation study based in Durban, South Africa, enrolled women aged 16-40 years from postrape care services, and a control group of women from Primary Healthcare services. Women who were HIV negative at baseline (441 in the rape-exposed group and 578 in the control group) were followed for 12-36 months with assessments every 3 months in the first year and every 6 months thereafter. Multivariable Cox regression models adjusted for baseline and time varying covariates were used to investigate the effect of rape exposure on HIV incidence over follow-up.Eighty-six women acquired HIV during 1605.5 total person-years of follow-up, with an incident rate of 6.6 per 100 person-years [95% confidence interval (CI): 4.8-9.1] among the rape exposed group and 4.7 per 100 person-years (95% CI: 3.5-6.2) among control group. After controlling for confounders (age, previous trauma, social support, perceived stress, multiple partners and transactional sex with a casual partner), women exposed to rape had a 60% increased risk of acquiring HIV [adjusted hazard ratio: 1.59 (95% CI: 1.01-2.48)] compared with those not exposed. Survival analysis showed difference in HIV incident occurred after month 9.Rape is a long-term risk factor for HIV acquisition. Rape survivors need both immediate and long-term HIV prevention and care.

Authors & Co-authors:  Abrahams Naeemah N Mhlongo Shibe S Dunkle Kristin K Chirwa Esnat E Lombard Carl C Seedat Soraya S Kengne Andre P AP Myers Bronwyn B Peer Nasheeta N Garcia-Moreno Claudia C Jewkes Rachel R

Study Outcome 

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Statistics
Citations :  Jewkes R. Gender inequities must be addressed in HIV prevention. Science 2010; 329:145–147.
Authors :  11
Identifiers
Doi : 10.1097/QAD.0000000000002779
SSN : 1473-5571
Study Population
Women
Mesh Terms
Adolescent
Other Terms
Study Design
Cohort Study,Case Control Trial,Cross Sectional Study
Study Approach
Country of Study
South Africa
Publication Country
England