Post-Stroke Psychiatric and Cognitive Symptoms in West Asia, South Asia and Africa: A Systematic Review and Meta-Analysis.

Journal: Journal of clinical medicine

Volume: 10

Issue: 16

Year of Publication: 

Affiliated Institutions:  Department of Behavioural Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat , Oman. Department of Family Medicine & Public Health, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat , Oman. Department of Rehabilitation Medicine in the Emory University School of Medicine, Clifton Road N.E., Atlanta, GA , USA. Department of Biochemistry, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat , Oman.

Abstract summary 

Recent research has shown that the prevalence of stroke incidents and the number of survivors in developing countries surpass those from developed countries. This study aimed to enumerate the prevalence of post-stroke psychiatric and cognitive symptoms among stroke survivors from West and South Asia and Africa through a systematic review and meta-analysis. Data from each country was systematically acquired from five major databases (PsycINFO, Web of Science, Scopus, PubMed/Medline, and Google Scholar (for any missing articles and grey literature)). Meta-analytic techniques were then used to estimate the prevalence of various post-stoke psychiatric and cognitive symptoms. A total of 36 articles were accrued from 11 countries, of which 25 were evaluated as part of the meta-analysis. The pooled prevalence of post-stroke depression as per the Hospital Anxiety and Depression Scale (HADS), Hamilton Depression Rating Scale, Patient Health Questionnaire, Schedules for Clinical Assessment in Neuropsychiatry (SCAN), Geriatric Depression Scale, and the Montgomery-Asberg Depression Rating Scale ranged from 28.00 to 50.24%. Pooled prevalence of post-stroke anxiety based on the HADS and SCAN was 44.19% and 10.96%, respectively. The pooled prevalence of post-stroke cognitive impairment as per the Mini-Mental Status Examination was 16.76%. This present review has suggested that both psychiatric and cognitive symptoms are common among stroke survivors. Concerted efforts are needed to institute robust studies using culturally sensitive measures to contemplate mechanisms that address the unmet needs of this vulnerable population.

Authors & Co-authors:  Mahadevan Sangeetha S Chan Moon Fai MF Moghadas Marzieh M Shetty Maithili M Burke David T DT Al-Rasadi Khalid K Al-Adawi Samir S

Study Outcome 

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Statistics
Citations :  Katan M., Luft A. Global Burden of Stroke. Semin. Neurol. 2018;38:208–211. doi: 10.1055/s-0038-1649503.
Authors :  7
Identifiers
Doi : 3655
SSN : 2077-0383
Study Population
Male,Female
Mesh Terms
Other Terms
Africa;South Asia;West Asia;anxiety;cognitive impairment;depression;meta-analysis;post-stroke;prevalence;systematic review
Study Design
Cross Sectional Study
Study Approach
Systemic Review
Country of Study
Publication Country
Switzerland