A mixed-methods, population-based study of a syndemic in Soweto, South Africa.

Journal: Nature human behaviour

Volume: 6

Issue: 1

Year of Publication: 2022

Affiliated Institutions:  Edmund A. Walsh School of Foreign Service, Georgetown University, Washington, DC, USA. em@georgetown.edu. SAMRC Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. Edmund A. Walsh School of Foreign Service, Georgetown University, Washington, DC, USA. Center for Global Health, Massachusetts General Hospital, Boston, MA, USA.

Abstract summary 

A syndemic has been theorized as a cluster of epidemics driven by harmful social and structural conditions wherein the interactions between the constitutive epidemics drive excess morbidity and mortality. We conducted a mixed-methods study to investigate a syndemic in Soweto, South Africa, consisting of a population-based quantitative survey (N = 783) and in-depth, qualitative interviews (N = 88). We used ethnographic methods to design a locally relevant measure of stress. Here we show that multimorbidity and stress interacted with each other to reduce quality of life. The paired qualitative analysis further explored how the quality-of-life impacts of multimorbidity were conditioned by study participants' illness experiences. Together, these findings underscore the importance of recognizing the social and structural drivers of stress and how they affect the experience of chronic illness and well-being.

Authors & Co-authors:  Mendenhall Emily E Kim Andrew Wooyoung AW Panasci Anthony A Cele Lindile L Mpondo Feziwe F Bosire Edna N EN Norris Shane A SA Tsai Alexander C AC

Study Outcome 

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Statistics
Citations :  Singer M, Bulled N, Ostrach B & Mendenhall E Syndemics and the Biosocial Conception of Health. Lancet 389, 941–50 (2017).
Authors :  8
Identifiers
Doi : 10.1038/s41562-021-01242-1
SSN : 2397-3374
Study Population
Male,Female
Mesh Terms
Adult
Other Terms
Study Design
Ethnographic Study,Cross Sectional Study
Study Approach
Quantitative,Qualitative
Country of Study
South Africa
Publication Country
England