Ring-ing in the Future: Participant and Male Partner Perspectives Regarding Future Use of the Dapivirine Vaginal Ring for HIV Prevention.

Journal: AIDS and behavior

Volume: 26

Issue: 6

Year of Publication: 2022

Affiliated Institutions:  Wits Reproductive Health and HIV Institute (Wits RHI), University of the Witwatersrand, Esselen Street, Hillbrow, Johannesburg, , South Africa. kreddy@wrhi.ac.za. Wits Reproductive Health and HIV Institute (Wits RHI), University of the Witwatersrand, Esselen Street, Hillbrow, Johannesburg, , South Africa. Women's Global Health Imperative (WGHI), RTI International, Berkeley, CA, USA. FHI , Durham, NC, USA. Centre for the AIDS Programme of Research in South Africa (CAPRISA), University of KwaZulu-Natal, Durban, South Africa. South African Medical Research Council, HIV Prevention Research Unit, KwaZulu-Natal, South Africa. University of Zimbabwe College of Health Sciences Clinical Trials Research Centre (UZCHS-CTRC), Harare, Zimbabwe. University of North Carolina (UNC) Project, Lilongwe, Malawi.

Abstract summary 

Women account for a disproportionate percentage of new HIV infections in sub-Saharan Africa indicating a need for female-initiated HIV prevention options congruent with their lifestyles. The dapivirine vaginal ring for HIV prevention is one such option. We explored the interest of women, who used this ring during the Microbicide Trials Network's ASPIRE and HOPE studies, in using the ring post-licensure and what they perceived as important considerations for future use. We also explored perspectives of HOPE participants' male partners on their involvement in their partners' future ring use. Women appeared keen to use the ring in the future and expressed desires for easy access, support for both ongoing and new users and intense community engagement. In parallel, male partners indicated high levels of interest in supporting their partners' ring use and being involved in ring use decision making. These data offer important insights for ring rollout planning and engagement activities.

Authors & Co-authors:  Reddy Krishnaveni K Mathebula Florence F Katz Ariana A Luecke Ellen E Tenza Siyanda S Palanee-Phillips Thesla T Garcia Morgan M Mansoor Leila E LE Naidoo Sarita S Morar Neetha N Chitukuta Miria M Tsidya Mercy M Montgomery Elizabeth T ET

Study Outcome 

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Citations :  Kharsany ABM, Karim QA. HIV infection and AIDS in Sub-Saharan Africa: Current status, Challenges and Opportunities. Open AIDS J. 2016;10:34–48.
Authors :  14
Identifiers
Doi : 10.1007/s10461-021-03542-z
SSN : 1573-3254
Study Population
Male,Women
Mesh Terms
Anti-HIV Agents
Other Terms
Dapivirine vaginal ring;Future use;HIV prevention
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
United States