Balance on the Brain: a randomised controlled trial evaluating the effect of a multimodal exercise programme on physical performance, falls, quality of life and cognition for people with mild cognitive impairment-study protocol.

Journal: BMJ open

Volume: 12

Issue: 4

Year of Publication: 2022

Affiliated Institutions:  Curtin School of Allied Health, Curtin University-Perth City Campus, Perth, Western Australia, Australia E.Burton@curtin.edu.au. Rehabilitation, Ageing and Independent Living (RAIL) Research Centre, School of Primary and Allied Health Care, Monash University, Clayton, Victoria, Australia. The Academic Unit for Psychiatry of Old Age, Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia. School of Allied Health, Western Australian Centre for Health and Ageing, The University of Western Australia, Perth, Western Australia, Australia. Next Step Health, Brisbane, Queensland, Australia. Curtin School of Population Health, Curtin University, Perth, Western Australia, Australia. Curtin School of Allied Health, Curtin University, Perth, Western Australia, Australia. Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. Department of Rehabilitation and Aged Care, Armadale Health Service, Armadale, Western Australia, Australia. Cognitive Clinic, Royal Perth Hospital, Perth, Western Australia, Australia. Physiotherapy Department, Adult Community and Allied Health Directorate, Rockingham Peel Group, Rockingham, Western Australia, Australia. Medical School, University of Western Australia, Perth, Western Australia, Australia. Neurosciences Unit, North Metropolitan Health Service Mental Health, Public Health and Dental Services, Perth, Western Australia, Australia. Neurogenetic Clinic and Physiotherapy Department, Royal Perth Hospital, Perth, Western Australia, Australia. Academic Unit of Psychiatry of Old Age, University of Melbourne, Melbourne, Victoria, Australia.

Abstract summary 

Exercise and physical activity have been shown to improve cognition for people living with mild cognitive impairment (MCI). There is strong evidence for the benefits of aerobic exercise and medium evidence for participating in regular strength training for people with MCI. However, people living with MCI fall two times as often as those without cognitive impairment and the evidence is currently unknown as to whether balance training for people with MCI is beneficial, as has been demonstrated for older people without cognitive impairment. The aim of this study is to determine whether a balance-focused multimodal exercise intervention improves balance and reduces falls for people with MCI, compared with a control group receiving usual care.This single blind randomised controlled trial (Balance on the Brain) will be offered to 396 people with MCI living in the community. The multimodal exercise intervention consists of two balance programmes and a walking programme to be delivered by physiotherapists over a 6-month intervention period. All participants will be followed up over 12 months (for the intervention group, this involves 6-month intervention and 6-month maintenance). The primary outcomes are (1) balance performance and (2) rate of falls. Physical performance, levels of physical activity and sedentary behaviour, quality of life and cognition are secondary outcomes. A health economic analysis will be undertaken to evaluate the cost-effectiveness of the intervention compared with usual care.Ethics approval has been received from the South Metropolitan Health Service Human Research Ethics Committee (HREC), Curtin University HREC and the Western Australia Department of Health HREC; and approval has been received to obtain data for health costings from Services Australia. The results will be disseminated through peer-review publications, conference presentations and online platforms.ACTRN12620001037998; Australian New Zealand Clinical Trials Registry (ANZCTR).

Authors & Co-authors:  Burton Elissa E Hill Keith K Ellis Kathryn A KA Hill Anne-Marie AM Lowry Meggen M Moorin Rachael R McVeigh Joanne A JA Jacques Angela A Erickson Kirk I KI Tate Joel J Bernard Sarah S Orr Carolyn F CF Bongiascia Luke L Clarnette Roger R Clark Melanie L ML Williams Shannon S Lautenschlager Nicola N

Study Outcome 

Source Link: Visit source

Statistics
Citations :  Plassman BL, Langa KM, McCammon RJ, et al. . Incidence of dementia and cognitive impairment, not dementia in the United States. Ann Neurol 2011;70:418–26. 10.1002/ana.22362
Authors :  17
Identifiers
Doi : e054725
SSN : 2044-6055
Study Population
Male,Female
Mesh Terms
Aged
Other Terms
preventive medicine;public health;rehabilitation medicine
Study Design
Case Control Trial,Cross Sectional Study
Study Approach
Country of Study
Publication Country
England