Work difficulties in people with multiple sclerosis: The role of anxiety, depression and coping.

Journal: Multiple sclerosis journal - experimental, translational and clinical

Volume: 8

Issue: 3

Year of Publication: 

Affiliated Institutions:  Department of Neurology, Elisabeth-TweeSteden Hospital, Tilburg, the Netherlands. Institute of Psychology, Health, Medical and Neuropsychology Unit, Leiden University, Leiden, the Netherlands. Department of Care Ethics, University of Humanistic Studies, Utrecht, the Netherlands. MS Research Institute, Nijmegen, the Netherlands. Tilburg School of Social and Behavioural Sciences, Tranzo Scientific Centre for Care and Welfare, Tilburg University, Tilburg, the Netherlands. Department of Rehabilitation Medicine, Centre for Rehabilitation, University of Groningen, University Medical Centre Groningen, Haren, the Netherlands. Department of Neurology, Medical Centre Leeuwarden, Leeuwarden, the Netherlands. Department of Neurology, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands. Department of Neurology, St Antonius Hospital, Nieuwegein, the Netherlands. Department of Neurology, Groene Hart Hospital, the Netherlands. Department of Neurology, NoordWest Ziekenhuisgroep, the Netherlands. Department of Neurology, Zuyderland Medical Centre, Sittard-Geleen, the Netherlands. Upendo MS Clinic, Boxtel, the Netherlands. Department of Neurology, Rijnstate Hospital, the Netherlands. Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands.

Abstract summary 

Symptoms of anxiety and depression affect the daily life of people with multiple sclerosis (MS). This study examined work difficulties and their relationship with anxiety, depression and coping style in people with MS.219 employed people with MS (median age  =  43 years, 79% female) completed questionnaires on anxiety, depression, coping style, demographics and work difficulties, and underwent a neurological examination. Two regression analyses were performed with work difficulties as the dependent variable and either anxiety or depression as continuous independent variables. Coping style, age, gender, educational level, MS-related disability and disease duration were added as additional predictors, as well as interaction terms between coping style and either symptoms of depression or anxiety.A significant model was found (   =  13.14,  < 0.001,   =  0.39) in which anxiety, emotion- and avoidance-oriented coping and MS-related disability were positively related to work difficulties. The analysis of depression resulted in a significant model (   =  14.98,  < 0.001,   =  0.42) in which depression, emotion- and avoidance-oriented coping and MS-related disability were positively related to work difficulties. None of the interaction effects were significant.Work difficulties were positively related to anxiety, depression, emotion- and avoidance-oriented coping and MS-related disability in workers with MS.

Authors & Co-authors:  van Egmond Eea E van der Hiele K K van Gorp Dam D Jongen P J PJ van der Klink Jjl J Reneman M F MF Beenakker Eac E van Eijk Jjj J Frequin Stfm S de Gans K K van Geel B M BM Gerlach Ohh O Hengstman Gjd G Mostert J P JP Verhagen Wim W Middelkoop Ham H Visser L H LH

Study Outcome 

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Statistics
Citations :  Boeschoten RE, Braamse AMJ, Beekman ATF, et al. Prevalence of depression and anxiety in multiple sclerosis: a systematic review and meta-analysis. J Neurol Sci 2017; 372: 331–341.
Authors :  17
Identifiers
Doi : 20552173221116282
SSN : 2055-2173
Study Population
Male,Female
Mesh Terms
Other Terms
anxiety;coping behaviour;depression;employment;multiple sclerosis;work
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
United States