Evaluating construct and criterion validity of NeuroScreen in assessing neurocognition among hospitalized Ugandan first-episode psychosis patients.
Volume: 32
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Abstract summary
Neurocognitive impairment (NCI) is commonly exhibited among patients experiencing their first episode of psychosis. However, there are few resources in many low-income countries, such as Uganda, that allow for the administration of extensive neurocognitive test batteries for the detection of NCI. is a brief tablet-based neurocognitive assessment battery that can be administered by all levels of healthcare staff. We examined the validity of to assess neurocognition and detect NCI in first-episode psychosis (FEP) patients in Uganda.We enrolled 112 participants FEP patients and matched controls at Butabika Mental Referral Hospital. Each participant completed and a traditionally administered neurocognitive battery: the MATRIC Consensus Cognitive Battery (MCCB). We examined correlations between participant performance on and the MCCB. A ROC curve determined sensitivity and specificity of to detect NCI as determined by MCCB criterion.There was a large, statistically significant correlation between overall performance on and the MCCB [(112) = 0.64, < .001]. Small to large correlations were found between tests in the MCCB and batteries. The ROC curve of performance to detect MCCB-defined NCI had an area under curve of 0.80 and optimal sensitivity and specificity of 83 % and 60 %, respectively.There was a moderate positive correlation between overall performance on both batteries. shows promise as a valid assessment battery to assess neurocognition and detect NCI in FEP patients in Uganda. Further studies of in healthy individuals and in a range of mental disorders are recommended.Study Outcome
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Citations : Aas M., Dazzan P., Mondelli V., Melle I., Murray R., Pariante C. A systematic review of cognitive function in first-episode psychosis, including a discussion on childhood trauma, stress, and inflammation. Frontiers in Psychiatry. 2014;4Authors : 14
Identifiers
Doi : 100276SSN : 2215-0013