Persistent morbidity in Clade IIb mpox patients: interim results of a long-term follow-up study, Belgium, June to November 2022.

Journal: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Volume: 28

Issue: 7

Year of Publication: 2023

Affiliated Institutions:  Institute of Tropical Medicine, Antwerp, Belgium. University of Cape Town, Cape Town, South Africa. These authors contributed equally to this work and share last authorship. The members of the study group are listed under Collaborators at the end of the article.

Abstract summary 

While mpox was well characterised during the 2022 global Clade IIb outbreak, little is known about persistent morbidity. We present interim results of a prospective cohort study of 95 mpox patients assessed 3-20 weeks post-symptom onset. Two-thirds of participants had residual morbidity, including 25 with persistent anorectal and 18 with genital symptoms. Loss of physical fitness, new-onset/worsened fatigue and mental health problems were reported in 36, 19 and 11 patients, respectively. These findings require attention by healthcare providers.

Authors & Co-authors:  Berens-Riha Nicole N Bracke Stefanie S Rutgers Jojanneke J Burm Christophe C Van Gestel Liesbeth L Hens Matilde M Kenyon Chris C Bottieau Emmanuel E Soentjens Patrick P Brosius Isabel I Van Esbroeck Marjan M Vercauteren Koen K van Griensven Johan J van Dijck Christophe C Liesenborghs Laurens L

Study Outcome 

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Statistics
Citations :  Patrocinio-Jesus R, Peruzzu F. Monkeypox Genital Lesions. N Engl J Med. 2022;387(1):66. 10.1056/NEJMicm2206893
Authors :  17
Identifiers
Doi : 2300072
SSN : 1560-7917
Study Population
Male,Female
Mesh Terms
Humans
Other Terms
fatigue;follow-up;long-term follow-up;medium-term follow-up;monkeypox;mpox;sequelae
Study Design
Cohort Study,Cross Sectional Study
Study Approach
Country of Study
Publication Country
Sweden