The relationship between alcohol consumption and risk of HIV in married men in Sub-Saharan Africa.

Journal: AIDS (London, England)

Volume: 38

Issue: 5

Year of Publication: 2024

Affiliated Institutions:  Heidelberg Institute of Global Health (HIGH), Medical Faculty and University Hospital, Heidelberg University, Heidelberg. Mental Health, Alcohol, Substance use and Tobacco Research Unit, South African Medical Research Council. Institute for Mental Health Policy Research, Centre for Addiction and Mental Health.

Abstract summary 

A key factor for incidence of HIV is alcohol consumption. It impacts judgment and the probability to overlook risk-relevant information, which creates a pathway to reduced adherence to biomedical prevention and engagement in condomless sex. We strengthen the understanding of the link between alcohol consumption and risk of HIV among married men in sub-Saharan Africa (SSA), as we use comprehensive population-level data to provide robust evidence with high external validity.Cross-sectional data analysis.Based on data from Demographic and Health Surveys (DHS) from 20 countries and over 30 000 observations, a minimally and a fully adjusted model with country fixed effects examined the relationship between the men's alcohol consumption (observed by wife) and HIV status (blood test) while accounting for survey weights and controlling for potential confounders.The data comprised a total of 35 108 men. Minimally adjusted [risk ratio (RR) 1.25; 95% confidence interval (CI) 1.14-1.37; P  < 0.001] and fully adjusted (RR 1.26; 95% CI 1.15-1.38; P  < 0.001) models showed a positive association between the men's alcohol consumption and HIV status. Two sensitivity analyses confirmed the association.In line with previous experimental studies and theoretical framework, this study confirms a risk relationship between alcohol consumption and HIV. Thus, modern HIV/AIDS programs must continue to address the relationship in implementation of prevention and treatment programs.

Authors & Co-authors:  König Lukas L Petersen Williams Petal P Shuper Paul A PA Probst Charlotte C

Study Outcome 

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Statistics
Citations :  GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017 . Lancet 2018; 392:1736–1788.
Authors :  4
Identifiers
Doi : 10.1097/QAD.0000000000003815
SSN : 1473-5571
Study Population
Men,Male
Mesh Terms
Male
Other Terms
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
England