Intermittent explosive disorder subtypes in the general population: association with comorbidity, impairment and suicidality.

Journal: Epidemiology and psychiatric sciences

Volume: 29

Issue: 

Year of Publication: 2020

Affiliated Institutions:  Department of Psychological Medicine, Dunedin School of Medicine, University of Otago, PO Box , Dunedin, New Zealand. Department of Developmental Psychology, Rijksuniversiteit Groningen, Groningen, Netherlands. Center for Reducing Health Disparities, UC Davis Health System, Sacramento, California, USA. College of Medicine, Al-Qadisiya University, Diwaniya governorate, Iraq. Health Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain. Department of Psychiatry, Stony Brook University School of Medicine, Stony Brook, New York, USA. School of Psychology, Ulster University, Londonderry, UK. Lisbon Institute of Global Mental Health and Chronic Diseases Research Center (CEDOC), NOVA Medical School | Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal. Anxiety Disorders Center, Buenos Aires, Argentina. National School of Public Health, Management and Development, Bucharest, Romania. Department of Psychiatry, University College Hospital, Ibadan, Nigeria. Shenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China. Department of Psychiatry and Clinical Psychology, Faculty of Medicine, Balamand University, Beirut, Lebanon. Institute for Development Research Advocacy and Applied Care (IDRAAC), Beirut, Lebanon. Department of Mental Health, School of Public Health, The University of Tokyo, Tokyo, Japan. Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA. Department of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong. Queensland Centre for Mental Health Research, The Park Centre for Mental Health, WacolQLD , Australia. Department of Psychiatry, College of Medicine, University of Ibadan; University College Hospital, Ibadan, Nigeria (Bibiloba). Faculty of Social Sciences, Colegio Mayor de Cundinamarca University, Bogota, Colombia. Department of Psychiatry & Mental Health and South African Medical Council Research Unit on Risk and Resilience in Mental Disorders, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa. Department of Mental Health, National Center of Public Health and Analyses, Sofia, Bulgaria.

Abstract summary 

Intermittent explosive disorder (IED) is characterised by impulsive anger attacks that vary greatly across individuals in severity and consequence. Understanding IED subtypes has been limited by lack of large, general population datasets including assessment of IED. Using the 17-country World Mental Health surveys dataset, this study examined whether behavioural subtypes of IED are associated with differing patterns of comorbidity, suicidality and functional impairment.IED was assessed using the Composite International Diagnostic Interview in the World Mental Health surveys (n = 45 266). Five behavioural subtypes were created based on type of anger attack. Logistic regression assessed association of these subtypes with lifetime comorbidity, lifetime suicidality and 12-month functional impairment.The lifetime prevalence of IED in all countries was 0.8% (s.e.: 0.0). The two subtypes involving anger attacks that harmed people ('hurt people only' and 'destroy property and hurt people'), collectively comprising 73% of those with IED, were characterised by high rates of externalising comorbid disorders. The remaining three subtypes involving anger attacks that destroyed property only, destroyed property and threatened people, and threatened people only, were characterised by higher rates of internalising than externalising comorbid disorders. Suicidal behaviour did not vary across the five behavioural subtypes but was higher among those with (v. those without) comorbid disorders, and among those who perpetrated more violent assaults.The most common IED behavioural subtypes in these general population samples are associated with high rates of externalising disorders. This contrasts with the findings from clinical studies of IED, which observe a preponderance of internalising disorder comorbidity. This disparity in findings across population and clinical studies, together with the marked heterogeneity that characterises the diagnostic entity of IED, suggests that it is a disorder that requires much greater research.

Authors & Co-authors:  Scott K M KM de Vries Y A YA Aguilar-Gaxiola S S Al-Hamzawi A A Alonso J J Bromet E J EJ Bunting B B Caldas-de-Almeida J M JM Cía A A Florescu S S Gureje O O Hu C-Y CY Karam E G EG Karam A A Kawakami N N Kessler R C RC Lee S S McGrath J J Oladeji B B Posada-Villa J J Stein D J DJ Zarkov Z Z de Jonge P P

Study Outcome 

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Statistics
Citations :  Babcock JC, Tharp ALT, Sharp C, Heppner W and Stanford MS (2014) Similarities and differences in impulsive/premeditated and reactive/proactive bimodal classifications of aggression. Aggression and Violent Behavior 19, 251–262.
Authors :  24
Identifiers
Doi : e138
SSN : 2045-7979
Study Population
Male,Female
Mesh Terms
Adult
Other Terms
Comorbidity;Intermittent Explosive Disorder;World Mental Health Surveys;impairment;suicidality
Study Design
Cross Sectional Study
Study Approach
Country of Study
Publication Country
England