Chronic HIV infection and health related quality of life in resource poor settings-an assessment from South East Nigeria.

Journal: African health sciences

Volume: 20

Issue: 1

Year of Publication: 2021

Affiliated Institutions:  Sub-Department of Dermatology, College of Medicine, University of Nigeria, Ituku-Ozalla Campus, Enugu, Nigeria. Department of Anaesthesia/Pain and palliative Care Unit, Multidisciplinary Oncology Center, College of Medicine, UNTH, Ituku-Ozalla Campus, Enugu, Nigeria. Department of Medicine, College of Medicine, University of Nigeria, Ituku-Ozalla Campus, Enugu, Nigeria. Federal Neuropsychiatric Hospital, Enugu, Nigeria. Urology Unit, Department of Surgery, College of Medicine, University of Nigeria, Ituku-Ozalla Campus, Enugu, Nigeria. Department of Medicine, University of Nigeria Teaching Hospital, Ituku-Ozalla. Department of Medical Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu, Nigeria.

Abstract summary 

Health-related quality of life reflects a patient's general subjective perception of the effect of an illness or intervention on physical, psychological and social aspects of daily life. HIV infection is a major public health problem especially in developing countries where poor health infrastructure and poverty are prevalent. This paper addresses the quality of life in patients with chronic HIV infection in South East Nigeria and addresses issues that may help improve the current situation.A cross-sectional survey was carried out at the University of Nigeria Teaching Hospital, Enugu, to assess patients with HIV receiving antiretroviral therapy (ART) using a validated structured questionnaire (WHOQoL-BREF). Ethical clearance for the study was obtained. Study period was from October - December, 2017. Data obtained was analysed.A total of 389 HIV patients consented to the study. Over 70% were aged 18- 45 years and majority were females. Females had a higher quality of life score with respect to the domain of psychological health while males had a higher score with respect to the environmental domain. Older age and presence of co-morbidities were significantly associated with affectation of physical health while younger age was associated with affectation of psychological health domain.HIV impairs the quality of life for affected individuals in South East Nigeria especially across the domains of physical and psychological health. No age group is spared. The presence of co-morbidities significantly reduces quality of life in these patients. Younger patients may require mental health services in the management of their disease.

Authors & Co-authors:  Onyekonwu Chinwe Laura CL Onyeka Tonia Chinyelu TC Brenda Nwatu Chidimma NC Ijoma Uchenna Nkemdilim UN Unaogu Ngozichukwu Nneka NN Onwuekwe Ikenna Obinwanne IO Ugwumba Fred F Nwutobo Chidimma Rhoda CR Nwachukwu Chioma Victoria CV

Study Outcome 

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Statistics
Citations :  Deeks SG, Lewin SR, Havlir DV. The End of AIDS: HIV Infection as a Chronic Disease. Lancet. 2013 Nov 2;382(9903):1525–1533.
Authors :  9
Identifiers
Doi : 10.4314/ahs.v20i1.15
SSN : 1729-0503
Study Population
Males,Females
Mesh Terms
Adolescent
Other Terms
HIV;South East Nigeria;quality of life
Study Design
Cross Sectional Study
Study Approach
Country of Study
Niger
Publication Country
Uganda