Previous disorders and depression outcomes in individuals with 12-month major depressive disorder in the World Mental Health surveys.
Journal: Epidemiology and psychiatric sciences
Volume: 30
Issue:
Year of Publication: 2021
Affiliated Institutions:
Department of Developmental Psychology, University of Groningen, Groningen, The Netherlands.
College of Medicine, Al-Qadisiya University, Diwaniya Governorate, Iraq.
Health Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, Barcelona, Spain.
Department of Psychiatry, University of Ibadan, Ibadan, Nigeria.
Universitair Psychiatrisch Centrum - Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg, Leuven, Belgium.
School of Psychology, Ulster University, Londonderry, UK.
Lisbon Institute of Global Mental Health and Chronic Diseases Research Center (CEDOC), NOVA Medical School|Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal.
IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia.
National School of Public Health, Management and Development, Bucharest, Romania.
Department of Psychiatry, University College Hospital, Ibadan, Nigeria.
Parc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Sant Boi de Llobregat, Barcelona, Spain.
Shenzhen Institute of Mental Health & Shenzhen Kangning Hospital, Shenzhen, China.
Department of Psychiatry and Clinical Psychology, St George Hospital University Medical Center, Beirut, Lebanon.
WSB University, Torun, Poland.
Ecole des Hautes Etudes en Santé Publique (EHESP), EA , Paris Descartes University, Paris, France.
Department of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong.
Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol QLD, Australia.
National Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico.
UDIF-SM, Servicio Murciano de Salud. IMIB-Arrixaca. CIBERESP-Murcia, Región de Murcia, Spain.
Department of Mental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Instituto Nacional de Salud, Lima, Peru.
Colegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia.
Department of Psychological Medicine, University of Otago, Dunedin, Otago, New Zealand.
Departamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Department of Psychiatry & Mental Health and South African Medical Council Research Unit on Risk and Resilience in Mental Disorders, University of Cape Town and Groote Schuur Hospital, Cape Town, Republic of South Africa.
Center for Excellence on Research in Mental Health, CES University, Medellin, Colombia.
Department of Social Medicine, Postgraduate Program in Public Health, Federal University of Espírito Santo, Vitoria, Brazil.
Department of Mental Health, National Center of Public Health and Analyses, Sofia, Bulgaria.
Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.
Abstract summary
Major depressive disorder (MDD) is characterised by a recurrent course and high comorbidity rates. A lifespan perspective may therefore provide important information regarding health outcomes. The aim of the present study is to examine mental disorders that preceded 12-month MDD diagnosis and the impact of these disorders on depression outcomes.Data came from 29 cross-sectional community epidemiological surveys of adults in 27 countries (n = 80 190). The Composite International Diagnostic Interview (CIDI) was used to assess 12-month MDD and lifetime DSM-IV disorders with onset prior to the respondent's age at interview. Disorders were grouped into depressive distress disorders, non-depressive distress disorders, fear disorders and externalising disorders. Depression outcomes included 12-month suicidality, days out of role and impairment in role functioning.Among respondents with 12-month MDD, 94.9% (s.e. = 0.4) had at least one prior disorder (including previous MDD), and 64.6% (s.e. = 0.9) had at least one prior, non-MDD disorder. Previous non-depressive distress, fear and externalising disorders, but not depressive distress disorders, predicted higher impairment (OR = 1.4-1.6) and suicidality (OR = 1.5-2.5), after adjustment for sociodemographic variables. Further adjustment for MDD characteristics weakened, but did not eliminate, these associations. Associations were largely driven by current comorbidities, but both remitted and current externalising disorders predicted suicidality among respondents with 12-month MDD.These results illustrate the importance of careful psychiatric history taking regarding current anxiety disorders and lifetime externalising disorders in individuals with MDD.
Authors & Co-authors:
Roest Annelieke M AM
de Vries Ymkje Anna YA
Al-Hamzawi Ali A
Alonso Jordi J
Ayinde Olatunde O OO
Bruffaerts Ronny R
Bunting Brendan B
Caldas de Almeida José Miguel JM
de Girolamo Giovanni G
Degenhardt Louisa L
Florescu Silvia S
Gureje Oye O
Haro Josep Maria JM
Hu Chiyi C
Karam Elie G EG
Kiejna Andrzej A
Kovess-Masfety Viviane V
Lee Sing S
McGrath John J JJ
Medina-Mora Maria Elena ME
Navarro-Mateu Fernando F
Nishi Daisuke D
Piazza Marina M
Posada-Villa José J
Scott Kate M KM
Stagnaro Juan Carlos JC
Stein Dan J DJ
Torres Yolanda Y
Viana Maria Carmen MC
Zarkov Zahari Z
Kessler Ronald C RC
de Jonge Peter P
Study Outcome
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