Diabetes mellitus and its association with central obesity and disability among older adults: a global perspective.

Journal: Experimental gerontology

Volume: 64

Issue: 

Year of Publication: 2015

Affiliated Institutions:  Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, Dr. Antoni Pujades, , Sant Boi de Llobregat, Barcelona, Spain; Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Monforte de Lemos -, Pabellón , Madrid, Spain. Pharmacy Department, Hospital de la Santa Creu i Sant Pau, Institut d'Investigacions Biomèdiques Sant Pau (IIB Sant Pau), Sant Antoni Maria Claret , Barcelona, Spain; Universitat Autònoma de Barcelona, Bellaterra Cerdanyola del Vallès, Spain. Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Monforte de Lemos -, Pabellón , Madrid, Spain; Department of Psychiatry, Universidad Autónoma de Madrid, Instituto de Investigación Sanitaria Princesa (IP), Hospital Universitario la Princesa, Madrid, Spain. Department of Health Statistics and Information Systems, World Health Organization, Geneva, Switzerland. Department of Medical Sociology, Jagiellonian University Medical College, Krakow, Poland. National Institute for Health and Welfare, Helsinki, Finland. Neurology, Public Health and Disability Unit, Neurological Institute "Carlo Besta" Foundation IRCCS (Istituto di ricovero e cura a carattere scientifico), Milan, Italy. Parc Sanitari Sant Joan de Déu, Universitat de Barcelona, Fundació Sant Joan de Déu, Dr. Antoni Pujades, , Sant Boi de Llobregat, Barcelona, Spain; Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Monforte de Lemos -, Pabellón , Madrid, Spain. Electronic address: jmharo@pssjd.org.

Abstract summary 

The aim of the study was to evaluate the association between various factors and diabetes type II (DM) with a particular emphasis on indicators of central obesity, and to compare the effect of DM on disability among elder populations (≥ 50 years old) in nine countries. Data were available for 52,946 people aged ≥ 18 years who participated in the WHO Study on global AGEing and adult health and the Collaborative Research on Ageing in Europe studies conducted between 2007 and 2012. DM was defined as self-report of physician diagnosis. Height, weight, and waist circumference were measured. Disability status was assessed with the WHODAS II questionnaire. The overall prevalence of DM was 7.9% and ranged from 3.8% (Ghana) to 17.6% (Mexico). A 10 cm increase in waist circumference and waist-to-height ratio of >0.5 were associated with a significant 1.26 (India) to 1.77 (Finland), and 1.68 (China, Spain) to 5.40 (Finland) times higher odds for DM respectively. No significant associations were observed in Mexico and South Africa. DM was associated with significantly higher disability status in all countries except Mexico in the model adjusted for demographics and smoking. The inclusion of chronic conditions associated with diabetes in the model attenuated the coefficients in varying degrees depending on the country. A considerable proportion of the studied older population had DM. Central obesity may be a key factor for the prevention of DM among older populations globally. Prevention of DM especially among the older population globally may contribute to reducing the burden of disability.

Authors & Co-authors:  Tyrovolas Stefanos S Koyanagi Ai A Garin Noe N Olaya Beatriz B Ayuso-Mateos Jose Luis JL Miret Marta M Chatterji Somnath S Tobiasz-Adamczyk Beata B Koskinen Seppo S Leonardi Matilde M Haro Josep Maria JM

Study Outcome 

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Statistics
Citations : 
Authors :  11
Identifiers
Doi : 10.1016/j.exger.2015.02.010
SSN : 1873-6815
Study Population
Male,Female
Mesh Terms
Age Factors
Other Terms
Diabetes mellitus;Disability;Obesity;Older adults;Waist circumference;Waist-to-height ratio
Study Design
Cross Sectional Study
Study Approach
Country of Study
Ghana
Publication Country
England