Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature.

Journal: Case reports in pulmonology

Volume: 2015

Issue: 

Year of Publication: 2015

Affiliated Institutions:  Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY , USA. St. George's University, School of Medicine, Grenada. Coney Island Hospital, Pulmonary Medicine, Brooklyn, NY , USA. Department of Obstetrics and Gynecology, Lincoln Medical and Mental Health Center, Bronx, NY , USA ; Cornell Medical College, NY , USA.

Abstract summary 

Background. Tuberculosis (TB) is a disease that affects hundreds of millions of people across the world. However, the incidence in developed countries has decreased over the past decades causing physicians to become unfamiliar with its unspecific symptoms. Pregnant individuals are especially difficult because many symptoms of active TB can mimic normal physiological changes of pregnancy. We present a case report of a 26-year-old multiparous woman, G4P3003, at 38-week gestation with a history of positive PPD who emigrated from Ghana 6 years ago. She came to the hospital with an initial complaint of suprapubic pain, pressure, and possible leakage of amniotic fluid for the past week. Patient also complained of a productive cough for the past 3 to 4 months with a decrease in vision occurring with the start of pregnancy. Visual acuity was worse than 20/200 in both eyes. Definitive diagnosis of active TB was delayed due to patient refusal of chest X-ray. Fortunately, delay in diagnosis was minimized since patient delivered within 24 hours of admission. Active TB was confirmed with intraocular dissemination. Patient had optic atrophy OS (left eye) and papillitis, choroiditis, and uveitis OD (right eye) due to TB infiltration. Fetus was asymptomatic and anti-TB therapy was started for both patients.

Authors & Co-authors:  Rezai Shadi S LoBue Stephen S Adams Daniel D Oladipo Yewande Y Posso Ramses R Mapp Tiffany T Santiago Crystal C Jain Manisha M Marino William D WD Henderson Cassandra E CE

Study Outcome 

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Statistics
Citations :  World Health Organization. Global Tuberculosis Report 2014. Geneva, Switzerland: WHO; 2014.
Authors :  10
Identifiers
Doi : 370462
SSN : 2090-6846
Study Population
Male,Female
Mesh Terms
Other Terms
Study Design
Case Study,Cross Sectional Study
Study Approach
Country of Study
Ghana
Publication Country
United States