Screening HIV-associated neurocognitive disorders (HAND) among HIV positive patients attending antiretroviral therapy in South Wollo, Ethiopia.

Journal: Journal of psychiatric research

Volume: 85

Issue: 

Year of Publication: 2017

Affiliated Institutions:  Department of Psychiatry, Dessie Referral Hospital, Dessie, Ethiopia. Electronic address: milliontse@gmail.com. Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia. Electronic address: gashawab@gmail.com. Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia. Electronic address: gechtop@gmail.com. Bahir Dar University, College of Medicine and Health Science, Bahir Dar, Ethiopia. Electronic address: minale@gmail.com.

Abstract summary 

The vast majority of people living with HIV/AIDS reside in low and middle income countries, particularly in Sub-Saharan Africa, including Ethiopia. Despite the huge number of service users in the local area, cognitive disorder among HIV patients has not been extensively studied and there is a dearth of knowledge on the subject. The objective of this study was to assess the prevalence and associated factors of HIV-associated neurocognitive disorder among people living with HIV/AIDS in antiretroviral therapy (ART) clinics.Institution based cross sectional study was conducted from April to May, 2015 at Dessie Referral Hospital & Kombolcha Health Center. International HIV Dementia Scale was used to screen HIV associated neurocognitive deficits. Logistic regression analysis was used to assess predictors of neurocognitive disorders.The risk of HIV associated neurocognitive disorder was 36.4%. Those who had CD4 count of 500 cells/dl or less (AOR = 2.368 (1.524, 3.680)), no formal education (AOR = 4.287 (2.619, 7.016)), poor medication adherence (AOR = 1.487 (1.010, 2.180)) and older age (AOR = 3.309 (1.259, 8.701)) were found to be significantly associated with HIV associated neurocognitive disorders.The risk of HIV-associated neurocognitive disorder was found to be high among people living with HIV/AIDS. This emphasizes the need of regular cognitive screening for early identification and appropriate intervention.

Authors & Co-authors:  Tsegaw Million M Andargie Gashaw G Alem Getnet G Tareke Minale M

Study Outcome 

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Citations : 
Authors :  4
Identifiers
Doi : 10.1016/j.jpsychires.2016.10.016
SSN : 1879-1379
Study Population
Male,Female
Mesh Terms
AIDS Dementia Complex
Other Terms
HIV;HIV-associated neurocognitive disorder;People living with HIV/AIDS
Study Design
Cross Sectional Study,
Study Approach
Country of Study
Ethiopia
Publication Country
England