Hypertensive disorders of pregnancy and the risk of anxiety disorders in adolescence: Findings from the Avon Longitudinal Study of Parents and Children.

Journal: Journal of psychiatric research

Volume: 110

Issue: 

Year of Publication: 2020

Affiliated Institutions:  Institute for Social Science Research, The University of Queensland, Brisbane, Australia; Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, Ethiopia. Electronic address: b.dachew@uqconnect.edu.au. Faculty of Medicine, School of Public Health, The University of Queensland, Herston, Australia; Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Wacol, Australia; Metro North Mental Health, Royal Brisbane and Women's Hospital, Herston, Australia. Institute for Social Science Research, The University of Queensland, Brisbane, Australia. Institute for Social Science Research, The University of Queensland, Brisbane, Australia; School of Public Health, Curtin University, Western Australia, Australia.

Abstract summary 

The effect of hypertensive disorders of pregnancy (HDP) on offspring anxiety disorders in adolescence is not yet known. This study aims to examine the association between HDP and offspring anxiety disorders at age 15 years.We used data from 5231 mother-offspring pairs from the United Kingdom based Avon Longitudinal Study of Parents and Children (ALSPAC). Anxiety disorder was diagnosed in the offspring at the age of 15 years using the Development and Well-Being Assessment (DAWBA).Among those who had anxiety disorders, 16.4% were exposed to HDP. After adjusting for a wide range of known confounders, we found that adolescents of women with HDP had a 2.43 fold (95% CI: 1.41-4.19) increase risk of anxiety disorders compared with adolescents of women without HDP.Our study showed that adolescents exposed to HDP had higher risk of anxiety disorders compared with unexposed adolescents and suggests that prevention and treatment of maternal HDP could possibly prevent offspring anxiety in adolescence. Early screening for anxiety disorders in offspring of women with HDP may also be warranted. Further research is needed to explain the pathways by which HDP may increase the risk of offspring psychopathology.

Authors & Co-authors:  Dachew Berihun Assefa BA Scott James G JG Mamun Abdullah A Alati Rosa R

Study Outcome 

Source Link: Visit source

Statistics
Citations : 
Authors :  4
Identifiers
Doi : 10.1016/j.jpsychires.2019.01.001
SSN : 1879-1379
Study Population
Women
Mesh Terms
Adolescent
Other Terms
ALSPAC;Adolescence;Anxiety disorders;Hypertensive disorders of pregnancy;Offspring
Study Design
Longitudinal Study,Cross Sectional Study
Study Approach
Country of Study
Publication Country
England