Impact of integrated district level mental health care on clinical and social outcomes of people with severe mental illness in rural Ethiopia: an intervention cohort study.

Journal: Epidemiology and psychiatric sciences

Volume: 29

Issue: 

Year of Publication: 2020

Affiliated Institutions:  Health Service and Population Research Department, King's College London, Institute of Psychiatry, Psychology and Neuroscience, Centre for Global Mental Health, London, UK. Addis Ababa University, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia. WHO Collaborating Centre for Mental Health Research and Capacity Building, Department of Psychiatry, Addis Ababa University, College of Health Sciences, School of Medicine, Addis Ababa, Ethiopia. Kotebe Metropolitan University, College of Education and Behavioral Studies, Addis Ababa, Ethiopia. Department of Psychiatry and Mental Health, Alan J Flisher Centre for Public Mental Health, University of Cape Town, Cape Town, Republic of South Africa. Division of Epidemiology and Public Health, University of Nottingham, School of Medicine, Nottingham, UK. Department of Global Health and Social Medicine, Harvard Medical School, Boston, USA.

Abstract summary 

There is limited evidence of the safety and impact of task-shared care for people with severe mental illnesses (SMI; psychotic disorders and bipolar disorder) in low-income countries. The aim of this study was to evaluate the safety and impact of a district-level plan for task-shared mental health care on 6 and 12-month clinical and social outcomes of people with SMI in rural southern Ethiopia.In the Programme for Improving Mental health carE, we conducted an intervention cohort study. Trained primary healthcare (PHC) workers assessed community referrals, diagnosed SMI and initiated treatment, with independent research diagnostic assessments by psychiatric nurses. Primary outcomes were symptom severity and disability. Secondary outcomes included discrimination and restraint.Almost all (94.5%) PHC worker diagnoses of SMI were verified by psychiatric nurses. All prescribing was within recommended dose limits. A total of 245 (81.7%) people with SMI were re-assessed at 12 months. Minimally adequate treatment was received by 29.8%. All clinical and social outcomes improved significantly. The impact on disability (standardised mean difference 0.50; 95% confidence interval (CI) 0.35-0.65) was greater than impact on symptom severity (standardised mean difference 0.28; 95% CI 0.13-0.44). Being restrained in the previous 12 months reduced from 25.3 to 10.6%, and discrimination scores reduced significantly.An integrated district level mental health care plan employing task-sharing safely addressed the large treatment gap for people with SMI in a rural, low-income country setting. Randomised controlled trials of differing models of task-shared care for people with SMI are warranted.

Authors & Co-authors:  Hanlon C C Medhin G G Selamu M M Birhane R R Dewey M M Tirfessa K K Garman E E Asher L L Thornicroft G G Patel V V Lund C C Prince M M Fekadu A A

Study Outcome 

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Statistics
Citations :  American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th Edition) (DSM-IV). Washington, DC: APA.
Authors :  13
Identifiers
Doi : e45
SSN : 2045-7979
Study Population
Male,Female
Mesh Terms
Adult
Other Terms
Bipolar disorder;community mental health;global mental health;psychotic disorder;schizophrenia;task-sharing
Study Design
Cohort Study,Cross Sectional Study
Study Approach
Country of Study
Ethiopia
Publication Country
England